Valsartan D8

Product Name Valsartan D8
Alternate Names Valsartan Stable Isotopes, Stable Isotopes of Valsartan
CAT No. CS-O-07051
CAS No. 1089736-72-0
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 443.57 g/mol
Mol. For. C₂₄H₂₁D₈N₅O₃
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Valsartan
Purity 95%
Therapeutic Anti-Hypertensives
Smileys [2H][C@@](C(=O)O)(C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(=O)CCCC
Canonical Smiles CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O
InchIKey ACWBQPMHZXGDFX-KFWZLTATSA-N
Inchl InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1/i2D3,3D3,16D,22D
IUPAC (2S)-2,3,4,4,4-pentadeuterio-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-3-(trideuteriomethyl)butanoic acid
Controlled No
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Valsartan D8 is a deuterated form of Valsartan, a medication used to treat high blood pressure, heart failure, and to reduce the risk of death after a heart attack. Valsartan D8 contains eight deuterium atoms, which can improve its pharmacokinetics by increasing its stability and reducing the rate of metabolism in the body. This can lead to a longer half-life and more consistent plasma concentration levels, resulting in improved therapeutic efficacy. Chemically, Valsartan D8 is an angiotensin II receptor antagonist. It works by blocking the binding of angiotensin II to its receptors, causing blood vessels to dilate and reducing blood pressure. This drug is metabolized by the liver and excreted through the kidneys. Valsartan D8 is administered orally, usually once or twice daily. The recommended dosage varies depending on the patient's age, weight, and medical condition. Common side effects of Valsartan D8 include dizziness, headache, fatigue, and diarrhea. In rare cases, it may cause allergic reactions, liver problems, or kidney failure. Overall, Valsartan D8 is a useful medication for treating high blood pressure and heart failure. Its deuterated form may offer improved pharmacokinetics and therapeutic efficacy. As with any medication, it should only be taken under the guidance of a healthcare professional.

Related Compounds

Valsartan D3 | Valsartan D9 |

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