Amlodipine EP Impurity B

Chemical Name Amlodipine EP Impurity B
Alternate Names Amlodipine Impurities, Impurities of Amlodipine
CAT No. CS-O-07174
CAS Registry# 721958-72-1
Category Impurities
Stock IN-Stock
Mol. Wt. 570.03 g/mol
Mol. For. C₂₉H₃₂ClN₃O₇
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amlodipine
Purity 95%
Therapeutic Anti-Hypertensives
Smileys O=C(C(C(C(C=CC=C1)=C1Cl)C(C(OC)=O)=C(C)N2)=C2COCCNC(C(C=CC=C3)=C3C(NC)=O)=O)OCC
Canonical Smiles CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCNC(=O)C3=CC=CC=C3C(=O)NC
InchIKey SNNCONCKJDOFKX-UHFFFAOYSA-N
Inchl InChI=1S/C29H32ClN3O7/c1-5-40-29(37)25-22(16-39-15-14-32-27(35)19-11-7-6-10-18(19)26(34)31-3)33-17(2)23(28(36)38-4)24(25)20-12-8-9-13-21(20)30/h6-13,24,33H,5,14-16H2,1-4H3,(H,31,34)(H,32,35)
IUPAC 5-O-ethyl 3-O-methyl 4-(2-chlorophenyl)-2-methyl-6-[2-[[2-(methylcarbamoyl)benzoyl]amino]ethoxymethyl]-1,4-dihydropyridine-3,5-dicarboxylate
Controlled No
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Amlodipine EP Impurity B is a chemical compound that is used in the pharmaceutical industry as a reference standard for the development and testing of drugs that contain Amlodipine. Amlodipine is a calcium channel blocker that is commonly used to treat hypertension, angina, and other cardiovascular diseases. The presence of impurities in Amlodipine can have adverse effects on the efficacy and safety of the drug, making the use of reference standards like Amlodipine EP Impurity B essential for ensuring the quality and purity of the final drug product. Chemically, Amlodipine EP Impurity B is known as (RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid dimethyl ester. It has a molecular weight of 444.95 g/mol and a melting point of 158-160°C. The compound is soluble in organic solvents like methanol and ethanol, but is insoluble in water. The use of Amlodipine EP Impurity B as a reference standard in drug development and testing ensures that the final drug product meets the required quality and purity standards. It enables pharmaceutical companies to accurately determine the concentration of impurities in Amlodipine and take appropriate measures to eliminate them.

Related Compounds

Amlodipine Related Compound A | Amlodipine EP Impurity E Maleate | Atorvastatin-Amlodipine Adduct | Amlodipine Impurity 8 | Amlodipine Besylate Impurity D Besylate salt | Hydroxyethyl phthalyl amlodipine | Amlodipine aminoethyl | Amlodipin EP Impurity D | Amlodipine EP Impurity F | Amlodipine Mannitol Adduct | Amlodipine Galactose Adduct | Dehydro Amlodipine N-Oxide | Dimethoxy Impurity Deschloro Amlodipine | Amlodipine Mannitol Adduct Acetate Salt | Amlodipine Impurity 38 | Amlodipine orotate | Amlodipine Impurity 25 | Amlodipine Impurity 29 | Amlodipine Nitroso Impurity | Amlodipine Lactose adduct | Amlodipine Azido Impurity | Amlodipine Impurity 61 | Amlodipine N-Lactoside | Amlodipine Impurity 19 | Amlodipine Impurity 34 | Phthaloyl Amlodipine Dimethyl Ester | Amlodipine Impurity 9 | Amlodipine Mannitol Adduct HCl Salt | R-Amlodipine Besilate | Amlodipine EP Impurity D HCl | Amlodipine Impurity 32 | Amlodipine Impurity | Amlodipine EP Impurity E | Amlodipine N-Galactose | Amlodipine For Peak Identification | Amlodipine Impurity F Maleate | Amlodipine EP Impurity C | Desmethyl Amlodipine | N-Fomyl Amlodipine | Amlodipine Aspartic Acid Impurity | N-Nitroso Amlodipine | Amlodipine EP Impurity D Oxalate Salt | Amlodipine EP Impurity G | Amlodipine morpholine impurity | Di-acid Amlodipine | Atorvastatin Amlodipine Dimer | N-Nitroso Amlodipine EP Impurity F | Deschloro Amlodipine | R-Amlodipine hemipentahydrate | Amlodipine EP Impurity H | Amlodipine EP Impurity A | Amlodipine Methyl Ester |

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