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Amoxicillin EP Impurity G is a chemical compound that is commonly used in the pharmaceutical industry as an impurity standard for the analysis and quality control of Amoxicillin formulations. It is also known as 2-(2-Amino-1,3-thiazol-4-yl)-2-(carboxymethyl)-5-methylpropane-1,3-diol or ATCM. This impurity is a degradation product of Amoxicillin, which is a widely used antibiotic.
The chemical formula of Amoxicillin EP Impurity G is C9H15N3O5S, and it has a molecular weight of 281.30 g/mol. It is a white to off-white powder that is soluble in water and has a melting point of around 175-180°C. The purity of this compound is typically measured by high-performance liquid chromatography (HPLC).
The presence of Amoxicillin EP Impurity G in Amoxicillin formulations can affect the potency and stability of the drug. Therefore, it is important to monitor and control the levels of this impurity during the manufacturing process. The permissible limit of this impurity is set by regulatory authorities, such as the European Pharmacopoeia (EP).
In summary, Amoxicillin EP Impurity G is a useful impurity standard for the quality control of Amoxicillin formulations. It is a degradation product of Amoxicillin and can affect the potency and stability of the drug. The permissible limit of this impurity is set by regulatory authorities, and its purity is typically measured by HPLC.
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