Atorvastatin EP Impurity E

Atorvastatin EP Impurity E, also known as Methyl 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methylmethanesulfonamido)methyl]pyridine-3-carboxylate, is a chemical compound that is commonly used in the pharmaceutical industry as a reference standard for quality control purposes. This impurity is typically found in small amounts in Atorvastatin, which is a popular drug used to lower cholesterol levels in patients with hypercholesterolemia. Atorvastatin EP Impurity E is a pyridine-based compound that contains a fluorophenyl group, a methyl group, and an isopropyl group. The compound has a molecular formula of C22H28FN2O4S and a molecular weight of 442.54 g/mol. It is a white to off-white powder that is sparingly soluble in water but highly soluble in organic solvents like methanol, ethanol, and acetone. In pharmaceutical applications, Atorvastatin EP Impurity E is used as a reference standard in the development and validation of analytical methods for the quantification of impurities in Atorvastatin. It is also used in the identification and characterization of impurities that may be present in Atorvastatin samples. The use of reference standards like Atorvastatin EP Impurity E ensures that pharmaceutical products are of consistent quality and purity, which is essential for patient safety and efficacy.