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Captopril EP Impurity A

Chemical Name Captopril EP Impurity A
CAT No. CS-O-07518
CAS Registry# 64806-05-9
Status Prompt Dispatch
Category Impurities
Mol. Wt. 432.55 g/mol
Mol. For. C₁₈H₂₈N₂O₆S₂
Hazardous This is a Hazardous Compound
COA View Sample COA

Additional Information


Controlled No
Therapeutic Anti-Hypertensives
Smileys CC(CSSCC(C)C(=O)N1CCCC1C(=O)O)C(=O)N2CCCC2C(=O)O
Hazardous Yes


Usage and description


Captopril EP Impurity A is a chemical compound that is commonly used in the pharmaceutical industry as a reference standard for quality control purposes. It is a known impurity of the drug Captopril, which is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and heart failure. Chemically, Captopril EP Impurity A is known as (S)-1-(2-Mercapto-1-oxopropyl)-L-proline, and it is typically synthesized through a multi-step chemical process involving the use of various reagents and solvents. In terms of usage, Captopril EP Impurity A is primarily used as a reference standard for analytical testing and method development in the pharmaceutical industry. It is also used as a marker for the identification and quantification of impurities in Captopril drug substances and finished products. From a chemical perspective, Captopril EP Impurity A is a proline derivative that contains a thiol (-SH) group, which is important for its reactivity and biological activity. The presence of this impurity in Captopril drug products can affect the drug's efficacy and safety, and thus it is important to monitor and control its levels during manufacturing and testing. Overall, Captopril EP Impurity A is an important compound in the pharmaceutical industry, and its proper characterization and control are critical for ensuring the quality and safety of Captopril drug products.

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