Sildenafil Impurity A

Product Name Sildenafil Impurity A
Alternate Names Sildenafil Impurities, Impurities of Sildenafil
CAT No. CS-O-08160
CAS No. 1391053-95-4
Category Impurities
Stock IN-Stock
Mol. Wt. 488.60 g/mol
Mol. For. C₂₃H₃₂N₆O₄S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Sildenafil
Purity Not less than 90 %
Therapeutic Erectile dysfunction
Smileys CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCN(CC2)C)C3=NC4=C(C(=O)N3)N(N=C4CC(C)C)C
Canonical Smiles CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCN(CC2)C)C3=NC4=C(C(=O)N3)N(N=C4CC(C)C)C
InchIKey MDDMCAQUTIFYAH-UHFFFAOYSA-N
Inchl InChI=1S/C23H32N6O4S/c1-6-33-19-8-7-16(34(31,32)29-11-9-27(4)10-12-29)14-17(19)22-24-20-18(13-15(2)3)26-28(5)21(20)23(30)25-22/h7-8,14-15H,6,9-13H2,1-5H3,(H,24,25,30)
IUPAC 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-(2-methylpropyl)-6H-pyrazolo[4,3-d]pyrimidin-7-one
Controlled No
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Sildenafil Impurity A is a chemical impurity that is commonly found in sildenafil citrate, which is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. This impurity is also known as N-desmethyl sildenafil, and it is a metabolite of sildenafil that is formed during the metabolism of the drug in the body. The usage of Sildenafil Impurity A is not intended for therapeutic purposes, but it is important to monitor the levels of this impurity in sildenafil citrate to ensure the safety and efficacy of the medication. The presence of this impurity can affect the potency and stability of sildenafil citrate, and it can also lead to potential side effects in patients. Therefore, pharmaceutical companies must adhere to strict guidelines and regulations to limit the amount of this impurity present in their products. From a chemical perspective, Sildenafil Impurity A is a white to off-white powder that is soluble in water and organic solvents. Its molecular formula is C21H30N6O4S, and its molecular weight is 474.57 g/mol. This impurity is structurally similar to sildenafil, but it lacks the pyrazolopyrimidinone ring that is present in the parent compound. In summary, Sildenafil Impurity A is a byproduct of sildenafil metabolism that can affect the quality of sildenafil citrate. Its presence must be carefully monitored and controlled to ensure the safety and efficacy of the medication.

Related Compounds

Propoxyphenyl Homohydroxysildenafil | Benzyl Sildenafil | Propoxyphenyl Sildenafil | Sildenafil Methyl Sulfonate Ester Impurity | Sildenafil Related Compound | Sildenafil EP Impurity D | Dimethylsildenafil | Sildenafil Citrate Impurity 3 | Sildenafil Chlorosulfone | Sildenafil Dimer Impurity | Thiohomo Sildenafil | Demethylpiperazinyl Iso Sildenafil Sulfonyl Chloride | De(methypiperazinyl) Sildenafil Dimer Impurity | Sildenafil open ring Impurity | Hydroxythiohomo Sildenafil | Nitroso-prodenafil | Sildenafil Impurity 3 | Demethylpiperazinyl Desethyl Sildenafil Sulfonyl Chloride | Demethylpiperazinyl 7-Desoxo 7-Thioxosildenafil Sulfonic Acid | Norneo Sildenafil | Hydroxyhomo Sildenafil | Sildenafil-N-Oxide | Pyrazole N-Demethyl Sildenafil | Propoxyphenyl-thiohydroxyhomosildenafil | Descarbonsildenafil | Desmethyl Thiosildenafil | Sildenafil Citrate Impurity-1 | Propoxyphenyl Thiosildenafil | O-Desethyl-O-propyl Methisosildenafil | N-Nitroso N-desmethyl Sildenafil | Sildenafil Citrate Impurity 2 | N-Nitroso Sildenafil | N-(Desmethyl)-tert-butyl Acetate Sildenafil | Sildenafil EP Impurity E |

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