Dacarbazine impurity B

Product Name Dacarbazine impurity B
Alternate Names Dacarbazine Impurities, Impurities of Dacarbazine
CAT No. CS-O-08271
CAS No. 360-97-4
Category Impurities
Stock IN-Stock
Mol. Wt. 126.12 g/mol
Mol. For. C₄H₆N₄O
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Dacarbazine
Purity Not less than 95 %
Therapeutic Anti-Cancer / Oncology
Smileys NC(C(N=CN1)=C1N)=O
Canonical Smiles C1=NC(=C(N1)C(=O)N)N
InchIKey DVNYTAVYBRSTGK-UHFFFAOYSA-N
Inchl InChI=1S/C4H6N4O/c5-3-2(4(6)9)7-1-8-3/h1H,5H2,(H2,6,9)(H,7,8)
IUPAC 4-amino-1H-imidazole-5-carboxamide
Controlled No
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Dacarbazine impurity B, also known as 5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR), is a purine nucleotide intermediate that is often used as a research tool in biochemistry and molecular biology. AICAR is a potent activator of AMP-activated protein kinase (AMPK), a key enzyme involved in cellular energy metabolism. It is also involved in the regulation of glucose uptake and fatty acid oxidation, making it a promising candidate for the treatment of metabolic disorders such as type 2 diabetes and obesity. In terms of chemical information, AICAR is a white to off-white crystalline powder with a molecular weight of 258.2 g/mol. It is soluble in water and has a pKa of 9.4. AICAR is stable under normal conditions, but can be degraded by exposure to light, heat, and moisture. AICAR is typically used in research settings as a tool to study the molecular mechanisms of metabolic regulation. It can also be used to stimulate fatty acid oxidation in skeletal muscle cells, which has potential applications in the treatment of obesity and related metabolic disorders. However, it should be noted that AICAR is not approved for human use and should only be used in laboratory settings by trained professionals.

Related Compounds

Dacarbazine Related Compound B | Dacarbazine Lactose Adduct Impurity | Dacarbazine EP Impurity A |

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