Topotecan Carboxylic Acid Sodium Salt
| Product Name | Topotecan Carboxylic Acid Sodium Salt |
|---|---|
| CAT No. | CS-O-08328 |
| CAS No. | 123949-08-6 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 461.44 g/mol |
| Mol. For. | C₂₃H₂₄N₃NaO₆ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CCC(C1=C(C(=O)N2CC3=CC4=C(C=CC(=C4CN(C)C)O)N=C3C2=C1)CO)(C(=O)[O-])O.[Na+] |
| Canonical Smiles | CCC(C1=C(C(=O)N2CC3=CC4=C(C=CC(=C4CN(C)C)O)N=C3C2=C1)CO)(C(=O)[O-])O.[Na+] |
| InchIKey | MKNSEUWGSSBVQF-BQAIUKQQSA-M |
| Inchl | InChI=1S/C23H25N3O6.Na/c1-4-23(32,22(30)31)16-8-18-20-12(9-26(18)21(29)15(16)11-27)7-13-14(10-25(2)3)19(28)6-5-17(13)24-20;/h5-8,27-28,32H,4,9-11H2,1-3H3,(H,30,31);/q;+1/p-1/t23-;/m0./s1 |
| IUPAC | sodium;(2S)-2-[1-[(dimethylamino)methyl]-2-hydroxy-8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Topotecan Carboxylic Acid Sodium Salt is a potent anticancer drug used in the treatment of various cancers, including ovarian, cervical, and small cell lung cancer. It is a water-soluble salt, which makes it easy to administer intravenously. Topotecan Carboxylic Acid Sodium Salt works by inhibiting the enzyme topoisomerase I, which is essential for DNA replication and repair. By preventing this enzyme from functioning correctly, the drug causes DNA damage, leading to cell death.
The chemical formula of Topotecan Carboxylic Acid Sodium Salt is C23H22N2NaO6, and its molecular weight is 448.42 g/mol. It is a white, crystalline powder that is highly soluble in water and slightly soluble in methanol.
Topotecan Carboxylic Acid Sodium Salt is typically administered as an intravenous infusion, with the dose and duration of treatment depending on the type and stage of cancer being treated. The drug is metabolized in the liver and excreted in the urine, with a half-life of approximately 3 hours.
While Topotecan Carboxylic Acid Sodium Salt is an effective anticancer drug, it does have some side effects, including nausea, vomiting, diarrhea, and myelosuppression (a decrease in the production of blood cells). Patients undergoing treatment with this drug may require regular blood tests to monitor their blood cell counts.
In conclusion, Topotecan Carboxylic Acid Sodium Salt is an important drug used in the treatment of various types of cancer. Its ability to inhibit topoisomerase I and cause DNA damage makes it a potent anticancer agent, although patients may experience side effects during treatment.
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