Nimesulide D5
| Product Name | Nimesulide D5 |
|---|---|
| Alternate Names | Nimesulide Stable Isotopes, Stable Isotopes of Nimesulide |
| CAT No. | CS-O-10081 |
| CAS No. | 1330180-22-7 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 313.34 g/mol |
| Mol. For. | C₁₃H₇D₅N₂O₅S |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Nimesulide |
| Purity | 95% |
| Smileys | CS(=O)(NC1=CC=C(C=C1OC2=C(C([2H])=C(C([2H])=C2[2H])[2H])[2H])[N+]([O-])=O)=O |
| Canonical Smiles | CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2 |
| InchIKey | HYWYRSMBCFDLJT-VIQYUKPQSA-N |
| Inchl | InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3/i2D,3D,4D,5D,6D |
| IUPAC | N-[4-nitro-2-(2,3,4,5,6-pentadeuteriophenoxy)phenyl]methanesulfonamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Nimesulide D5 is a deuterated form of Nimesulide, a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It is a selective cyclooxygenase-2 (COX-2) inhibitor, which means it specifically targets the enzyme responsible for inflammation and pain, without affecting the enzyme responsible for protecting the stomach lining.
Nimesulide D5 is used to treat a variety of conditions, including osteoarthritis, rheumatoid arthritis, and acute pain. It is also used to treat fever and pain associated with respiratory tract infections. The drug works by blocking the production of prostaglandins, which are responsible for inflammation and pain.
Chemically, Nimesulide D5 is a white to off-white crystalline powder, with a molecular weight of 314.39 g/mol. It is slightly soluble in water and ethanol, and has a melting point of 157-161°C. The deuterated form of Nimesulide is used in pharmacokinetic studies, where the deuterium atoms are used as tracers to track the metabolism of the drug in the body.
Nimesulide D5 should be taken as directed by a healthcare professional, as it can cause side effects such as gastrointestinal bleeding, liver damage, and allergic reactions. It should not be taken by individuals with a history of ulcers, bleeding disorders, or liver disease. Overall, Nimesulide D5 is a useful medication for treating pain and inflammation, and has a specific mechanism of action that reduces the risk of gastrointestinal side effects compared to other NSAIDs.
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Related Compounds
Nimesulide metabolite-D4 | Nimesulide 13C6 |