Nicardipine dimethyl ester
| Product Name | Nicardipine dimethyl ester |
|---|---|
| Alternate Names | Nicardipine Impurities, Impurities of Nicardipine |
| CAT No. | CS-O-10407 |
| CAS No. | 21881-77-6 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 346.33 g/mol |
| Mol. For. | C₁₇H₁₈N₂O₆ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Nicardipine |
| Purity | Not less than 90 % |
| Therapeutic | Anti-Hypertensives |
| Smileys | CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC |
| Canonical Smiles | CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC |
| InchIKey | MCTRZKAKODSRLQ-UHFFFAOYSA-N |
| Inchl | InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-6-5-7-12(8-11)19(22)23/h5-8,15,18H,1-4H3 |
| IUPAC | dimethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Nicardipine dimethyl ester is a potent calcium channel blocker that is used for the treatment of hypertension, angina, and other cardiovascular diseases. Its chemical formula is C26H32N2O6 and its molecular weight is 480.54 g/mol.
Nicardipine dimethyl ester works by inhibiting the influx of calcium ions into smooth muscle cells, which leads to a decrease in vascular tone and an increase in coronary blood flow. This reduces the workload on the heart and improves cardiac function, resulting in a decrease in blood pressure and relief of angina symptoms.
The drug is available in the form of tablets, injectables, and oral solutions, and is usually administered intravenously or orally. It is rapidly absorbed and metabolized in the liver, and its metabolites are excreted in the urine and feces.
Nicardipine dimethyl ester is generally well tolerated, but like all drugs, it can cause side effects such as dizziness, headache, nausea, and constipation. It should not be used in patients with severe hypotension, heart failure, or hepatic impairment.
In conclusion, Nicardipine dimethyl ester is an effective calcium channel blocker that is widely used for the treatment of cardiovascular diseases. Its mechanism of action, pharmacokinetics, and safety profile make it a valuable therapeutic option for patients with hypertension, angina, and other related conditions.
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Related Compounds
Nicardipine N-Oxide | Nicardipine impurity 4-MMNOC | Dehydro Nicardipine | Nicardipine impurity 2-MMNOC | Nicardipine Related Compound 2 | Nicardipine impurity MNC | Nicardipine Related Compound 4 | Nicardipine dimethyl ester analog | N-nitroso Nicardipine | Nicardipine N-Desbenzyl N-Nitroso Impurity | N-Nitroso N-desmethyl Nicardipine | Nicardipine EP Impurity B DiHCl | Nicardipine Diacetyl Derivative |