Clobetasol 17-Propionate-d5

Product Name Clobetasol 17-Propionate-d5
CAT No. CS-O-10430
CAS No. 25122-46-7(Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 472.00 g/mol
Mol. For. C₂₅H₂₇D₅ClFO₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Purity 95%
Smileys O=C(O[C@@]1(C(CCl)=O)[C@](C[C@@H]([C@]([C@@]2(C)C=CC3=O)([C@]4(CCC2=C3)[H])F)O)(C)[C@]4(C[C@@H]1C)[H])C([2H])([2H])C([2H])([2H])[2H]
Canonical Smiles CCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CCl
InchIKey CBGUOGMQLZIXBE-XGQKBEPLSA-N
Inchl InChI=1S/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1
IUPAC [(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Controlled No
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Clobetasol 17-Propionate-d5 is a potent topical corticosteroid used to treat inflammatory skin conditions such as eczema, psoriasis, dermatitis, and other skin disorders. It is a deuterated analog of clobetasol propionate, which means that five hydrogen atoms of the molecule have been replaced with deuterium atoms. This modification provides additional stability to the molecule, making it more resistant to metabolic degradation. Clobetasol 17-Propionate-d5 is available in cream, ointment, and solution formulations. It works by reducing inflammation and suppressing the immune response in the affected area, thereby relieving symptoms such as itching, redness, and swelling. The medication is applied to the affected area once or twice daily, as directed by a physician. Chemically, Clobetasol 17-Propionate-d5 is a synthetic corticosteroid that belongs to the class of glucocorticoids. It is a white crystalline powder with a molecular formula of C25H28D5ClF2O5 and a molecular weight of 504.05 g/mol. The medication is classified as a class I corticosteroid, which means it has the highest potency among topical corticosteroids. However, due to its high potency, it should not be used for prolonged periods or on large areas of skin as it may cause side effects such as skin thinning, stretch marks, and increased risk of infection. Overall, Clobetasol 17-Propionate-d5 is a highly effective medication for the treatment of inflammatory skin conditions when used appropriately under the guidance of a healthcare professional.

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