Nifedipine nitroso-d6
Also known as: Nifedipine Nitrosamine Impurities or nitrosamine impurities of Nifedipine| Product Name | Nifedipine nitroso-d6 |
|---|---|
| Alternate Names | Nifedipine Stable Isotopes, Stable Isotopes of Nifedipine |
| CAT No. | CS-O-10445 |
| CAS No. | 167710-84-1 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Nifedipine |
| Therapeutic | Anti-Hypertensives |
| Smileys | O=C(C(C(C(C=CC=C1)=C1N=O)C(C(OC([2H])([2H])[2H])=O)=C(C)N2)=C2C)OC([2H])([2H])[2H] |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
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| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Nifedipine nitroso-d6 is a deuterated analog of the calcium channel blocker Nifedipine. It is commonly used in pharmaceutical research and drug development to study the metabolism, pharmacokinetics, and pharmacodynamics of Nifedipine in vivo.
Nifedipine works by blocking the influx of calcium ions into vascular and cardiac muscle cells, leading to vasodilation and decreased blood pressure. As a deuterated analog, Nifedipine nitroso-d6 offers several advantages over its non-deuterated counterpart. Deuterium is a stable isotope of hydrogen, and replacing some of the hydrogen atoms with deuterium can alter the physicochemical properties of the compound, such as solubility, lipophilicity, and potency. This can lead to improved drug efficacy, safety, and selectivity.
In addition to its pharmacological applications, Nifedipine nitroso-d6 is also used as a reference standard in analytical chemistry, especially in mass spectrometry-based methods. The deuterium label allows for accurate quantification of Nifedipine and its metabolites in biological matrices, such as plasma, urine, and tissues.
The chemical formula of Nifedipine nitroso-d6 is C17H11D6N3O6, and its molecular weight is 383.35 g/mol. It is a yellow crystalline powder, soluble in organic solvents but insoluble in water. The compound should be handled with care, as it may cause skin and eye irritation.
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Related Compounds
Nifedipine dehydro nitroso-d6 | Dehydro Nifedipine D6 | m-Nifedipine-d6 | Nifedipine D6 | Dehydronifedipine 13C8 | Nifedipine 13C8 |