Monoacetyl Canagliflozin

Product Name Monoacetyl Canagliflozin
Alternate Names Canagliflozin Impurities, Impurities of Canagliflozin
CAT No. CS-O-10755
CAS No. 2146135-87-5
Category Impurities
Stock IN-Stock
Mol. Wt. 486.55 g/mol
Mol. For. C₂₆H₂₇FO₆S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Canagliflozin
Purity 99.96
Therapeutic Anti-Diabetic
Smileys O[C@H]1[C@H](O)[C@@H](CO[C][*])O[C@@H](C2=CC(CC3=CC=C(C4=CC=C(F)C=C4)S3)=C(C)C=C2)[C@@H]1O
Canonical Smiles CC1=C(C=C(C=C1)C2C(C(C(C(O2)COC(=O)C)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F
InchIKey RXTZJMBUUNMILB-ZGLCYIBRSA-N
Inchl InChI=1S/C26H27FO6S/c1-14-3-4-17(26-25(31)24(30)23(29)21(33-26)13-32-15(2)28)11-18(14)12-20-9-10-22(34-20)16-5-7-19(27)8-6-16/h3-11,21,23-26,29-31H,12-13H2,1-2H3/t21-,23-,24+,25-,26+/m1/s1
IUPAC [(2R,3S,4R,5R,6S)-6-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]-3,4,5-trihydroxyoxan-2-yl]methyl acetate
Controlled No
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Monoacetyl Canagliflozin is a medication used to manage type 2 diabetes. It works by inhibiting the sodium-glucose cotransporter 2 (SGLT2) in the kidneys, which reduces the amount of glucose reabsorbed by the body and increases its excretion through urine. This results in lower blood sugar levels and improved glycemic control. Chemically, Monoacetyl Canagliflozin is a white to off-white crystalline powder with a molecular weight of 453.5 g/mol. Its chemical formula is C24H25ClO7 and it has a melting point of 155-157°C. The recommended dosage of Monoacetyl Canagliflozin is 100 mg taken orally once daily, with or without food. It is important to follow the prescribed dosage and not to exceed it. Patients with renal impairment or those taking certain medications may require dose adjustments. Monoacetyl Canagliflozin may cause side effects such as dehydration, urinary tract infections, hypotension, and ketoacidosis. It is not recommended for patients with type 1 diabetes or diabetic ketoacidosis. It is also important to monitor blood glucose levels regularly while taking this medication. In conclusion, Monoacetyl Canagliflozin is a medication used to manage type 2 diabetes by inhibiting SGLT2 in the kidneys. It has a specific chemical formula and recommended dosage, but may cause side effects that need to be monitored.

Related Compounds

Canagliflozin impurity F | Canagliflozin Peroxide Impurity | Canagliflozin impurity 12 | Canagliflozin Impurity B | Desfluoro Canagliflozin | Canagliflozin α Isomer | Canagliflozin Open Ring Impurity | Canagliflozin 2,3-dehydroxy impurity | Canagliflozin Dimethoxy Impurity | Canagliflozin 2-Methyl Phenyl Impurity | TMS- Hydroxy Canagliflozin | Canagliflozin DI D-glucitol IMPURITY | Canagliflozin DIsulfOXIDE impurity | Canagliflozin impurity C | Canagliflozin Enantiomer impurity | Tetra Acetyl Canagliflozin | Canagliflozin impurity E | Canagliflozin Impurity 10 | Canagliflozin Impurity 22 | Canagliflozin impurity 11 | Canagliflozin Dimer-1 | Canagliflozin impurity D | Canagliflozin Impurity 20 | Canagliflozin R-Furanose | Canagliflozin Dimer | Canagliflozin-10 Lactol | Canagliflozin-S-Furanose | Canagliflozin Impurity 23 | Canagliflozin Hydroxy Impurity | Canagliflozin hydroperoxy impurity |

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