Posaconazole D4
| Product Name | Posaconazole D4 |
|---|---|
| Alternate Names | Posaconazole Stable Isotopes, Stable Isotopes of Posaconazole |
| CAT No. | CS-O-10954 |
| CAS No. | 1133712-26-1 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 704.80 g/mol |
| Mol. For. | C₃₇H₃₈D₄F₂N₈O₄ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Posaconazole |
| Purity | 95% |
| Therapeutic | Anti-Fungals |
| Smileys | [2H]C1=C(C(=C(C(=C1N2CCN(CC2)C3=CC=C(C=C3)OC[C@H]4C[C@](OC4)(CN5C=NC=N5)C6=C(C=C(C=C6)F)F)[2H])[2H])N7C=NN(C7=O)[C@@H](CC)[C@H](C)O)[2H] |
| Canonical Smiles | CCC(C(C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5CC(OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F |
| InchIKey | RAGOYPUPXAKGKH-YWOVKAAPSA-N |
| Inchl | InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1/i5D,6D,7D,8D |
| IUPAC | 2-[(2S,3S)-2-hydroxypentan-3-yl]-4-[2,3,5,6-tetradeuterio-4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Posaconazole D4 is a deuterated analog of posaconazole, which is a triazole antifungal agent used for the treatment of various fungal infections. The deuterium substitution in Posaconazole D4 provides a unique tool for pharmacokinetic and pharmacodynamic studies of posaconazole.
Posaconazole D4 is typically used in clinical studies as a stable isotope-labeled internal standard for the quantification of posaconazole in biological fluids and tissues. It is also used in research to investigate drug-drug interactions, metabolism, and pharmacokinetics of posaconazole.
The chemical formula of Posaconazole D4 is C37H41D4F2N5O4, and its molecular weight is 666.81 g/mol. It is a white to off-white powder with high purity and stability. The compound is soluble in organic solvents such as methanol, ethanol, and acetonitrile but insoluble in water.
Posaconazole D4 is synthesized through deuterium exchange reactions using labeled starting materials. The compound is then purified using chromatography techniques to obtain a high-quality product.
In conclusion, Posaconazole D4 is a valuable tool for pharmacokinetic and pharmacodynamic studies of posaconazole. Its unique properties allow for accurate quantification and investigation of the drug's metabolism and interactions, making it an essential component of research in antifungal therapy.
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Related Compounds
Posaconazole D3 | Posaconazole Impurity 22 | Posaconazole Diastereoisomer Related Compound 4 | Posaconazole Diastereoisomer Related Compound 3 | rac-Posaconazole Diastereoisomer Related Compound 3 | Posaconazole D5 | Posaconazole-d7 |