Acyclovir L-Isoleucinate

Product Name Acyclovir L-Isoleucinate
Alternate Names Acyclovir Impurities, Impurities of Acyclovir
CAT No. CS-O-10968
CAS No. 142963-63-1
Category Impurities
Stock IN-Stock
Mol. Wt. 338.36 g/mol
Mol. For. C₁₄H₂₂N₆O₄
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Acyclovir
Therapeutic Antiretroviral / Anti-HIV
Smileys O=C1C2=C(N=C(N)N1)N(C=N2)COCCOC([C@@H](N)[C@@H](C)CC)=O
Canonical Smiles CCC(C)C(C(=O)OCCOCN1C=NC2=C1N=C(NC2=O)N)N
InchIKey DYTMGBXTNHPPNK-IUCAKERBSA-N
Inchl InChI=1S/C14H22N6O4/c1-3-8(2)9(15)13(22)24-5-4-23-7-20-6-17-10-11(20)18-14(16)19-12(10)21/h6,8-9H,3-5,7,15H2,1-2H3,(H3,16,18,19,21)/t8-,9-/m0/s1
IUPAC 2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]ethyl (2S,3S)-2-amino-3-methylpentanoate
Controlled No
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Acyclovir L-Isoleucinate is an antiviral drug that is used to treat infections caused by the herpes simplex virus and the varicella-zoster virus. The drug works by inhibiting the replication of the virus, thereby preventing the spread of the infection. Acyclovir L-Isoleucinate is a prodrug of Acyclovir, which means that it is converted into Acyclovir in the body. The L-Isoleucine moiety improves the solubility and stability of the drug, making it more effective and easier to administer. The chemical formula of Acyclovir L-Isoleucinate is C20H34N5O6 and its molecular weight is 454.52 g/mol. The drug is administered intravenously and is rapidly converted into Acyclovir in the plasma. The half-life of Acyclovir L-Isoleucinate is approximately 2 hours, while the half-life of Acyclovir is approximately 3 hours. The drug is eliminated from the body primarily through the kidneys, with approximately 84% of the dose excreted unchanged. Acyclovir L-Isoleucinate is generally well-tolerated, with the most common side effects being nausea, vomiting, and diarrhea. The drug is contraindicated in patients with a known hypersensitivity to Acyclovir or any of its components. It should be used with caution in patients with renal impairment, as the drug is primarily excreted through the kidneys. Overall, Acyclovir L-Isoleucinate is an effective antiviral drug that is widely used in the treatment of herpes simplex virus and varicella-zoster virus infections.

Related Compounds

D-Valacyclovir | Acyclovir Impurity M | D-Valacyclovir Hydrochloride | Bis N-Benzyloxycarbonyl-6-O-benzyl valacyclovir | Acyclovir Impurity D | Acyclovir L-Alaninate | Valacyclovir Valine | Acyclovir Impurity L | Acyclovir Impurity E | Acyclovir EP Impurity R | guaninyl valacyclovir EP impurity N | Acyclovir Alaninate | Acyclovir L-Leucinate | Acyclovir N-Ethyl-L-valinate Hydrochloride | Acyclovir N-Methylene Dimer | Acyclovir Impurity C | Acyclovir Impurity A | Guaninyl Valacyclovir | Acyclovir Impurity F | Acyclovir Impurity-K + R | Acyclovir N-Methyl-L-valinate Hydrochloride | Acyclovir Impurity J | Acyclovir Impurity G | D-Valacyclovir Hydrochloride | Acyclovir EP Impurity Q (Mixture of Isomers) | Acyclovir Impurity H | Acyclovir Impurity P | Acyclovir Impurity K Disodium Salt | N-t-Boc Valacyclovir | Acyclovir Impurity O | Acyclovir Impurity I |

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