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Mono-POC Ethyl Tenofovir
| Chemical Name | Mono-POC Ethyl Tenofovir |
|---|---|
| CAT No. | CS-O-11174 |
| CAS Registry# | 1796539-92-8 |
| Status | Available for Immediate Dispatch |
| Category | Impurities |
| Mol. Wt. | 431.38 mol/g |
| Mol. For. | C16H26N5O7P |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
Additional Information
| Controlled | No |
|---|---|
| Parent API | Tenofovir |
| Purity | Not less than 90 % |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | C[C@@H](OC[P](OCOC(OC(C)C)=O)(OCC)=O)CN1C2=NC=NC(N)=C2N=C1 |
| Hazardous | Yes |
Usage and description
Mono-POC Ethyl Tenofovir is a novel prodrug of Tenofovir, which is used in the treatment of HIV and Hepatitis B virus infections. It is a nucleotide analog reverse transcriptase inhibitor that works by blocking the replication of the virus. Mono-POC Ethyl Tenofovir is designed to improve the bioavailability and pharmacokinetics of Tenofovir, thereby reducing the frequency of dosing and minimizing adverse effects.
The chemical structure of Mono-POC Ethyl Tenofovir consists of a phosphonamidate prodrug linked to a lipophilic ethyl group. The lipophilic nature of this compound allows for increased cellular uptake and better distribution into the target cells. The prodrug is selectively activated by esterases in the plasma and liver, releasing the active form of Tenofovir.
Mono-POC Ethyl Tenofovir is administered orally and has been studied in clinical trials for its safety and efficacy. It has shown promising results in reducing viral load and improving immune function in HIV-infected patients. Additionally, it has been found to be effective in the treatment of chronic Hepatitis B infections.
In conclusion, Mono-POC Ethyl Tenofovir is a prodrug of Tenofovir that has been designed to improve its bioavailability and pharmacokinetics. It has shown promising results in the treatment of HIV and Hepatitis B virus infections and may offer a safer and more effective alternative to current therapies.
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