Leflunomide-d4
| Product Name | Leflunomide-d4 |
|---|---|
| Alternate Names | Leflunomide Stable Isotopes, Stable Isotopes of Leflunomide |
| CAT No. | CS-O-11466 |
| CAS No. | 1189987-23-2 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 274.23 g/mol |
| Mol. For. | C₁₂H₅D₄F₃N₂O₂ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Leflunomide |
| Purity | 95% |
| Therapeutic | Immunosuppressants |
| Smileys | O=C(C(C=NO1)=C1C)NC(C([2H])=C2[2H])=C(C([2H])=C2C(F)(F)F)[2H] |
| Canonical Smiles | CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F |
| InchIKey | VHOGYURTWQBHIL-QFFDRWTDSA-N |
| Inchl | InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)/i2D,3D,4D,5D |
| IUPAC | 5-methyl-N-[2,3,5,6-tetradeuterio-4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Leflunomide-d4 is a deuterated version of Leflunomide, a disease-modifying antirheumatic drug (DMARD) that is used to treat rheumatoid arthritis. This medication works by suppressing the immune system and reducing inflammation in the joints, which helps to alleviate the pain and swelling associated with this condition. Leflunomide-d4 is a labeled internal standard used in the analysis of Leflunomide by mass spectrometry.
Chemically, Leflunomide-d4 is a white to off-white crystalline powder, with a molecular formula of C12H4D4ClF3N2O2. It is classified as an isoxazole derivative, and its chemical structure is similar to that of teriflunomide, another DMARD used to treat multiple sclerosis. Leflunomide-d4 has a melting point of 106-107°C and a purity of at least 98%.
Leflunomide-d4 is typically administered orally as a tablet, with a recommended dosage of 20mg per day for adults. It is metabolized in the liver to form its active metabolite, teriflunomide, which has a much longer half-life than Leflunomide-d4 itself. Leflunomide-d4 is excreted primarily in the feces, with a small amount being eliminated in the urine.
In conclusion, Leflunomide-d4 is a helpful tool in the analysis of Leflunomide by mass spectrometry, and its use can aid in the development and monitoring of therapeutic treatments for rheumatoid arthritis.
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Related Compounds
Leflunomide 13C6 |