Estrone-3-sulphate sodium

Product Name Estrone-3-sulphate sodium
Alternate Names Estrone Impurities, Impurities of Estrone
CAT No. CS-O-11642
CAS No. 438-67-5
Category Impurities
Stock IN-Stock
Mol. Wt. 373.42 g/mol
Mol. For. C₁₈H₂₂NaO₅S
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Estrone
Purity 95%
Smileys C[C@@]1(C2=O)[C@](CC2)([H])[C@@](CCC3=C4C=CC(O[S](=O)([O-])=O)=C3)([H])[C@]4([H])CC1.[Na+]
Canonical Smiles CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)[O-].[Na+]
InchIKey VUCAHVBMSFIGAI-ZFINNJDLSA-M
Inchl InChI=1S/C18H22O5S.Na/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);/q;+1/p-1/t14-,15-,16+,18+;/m1./s1
IUPAC sodium;[(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] sulfate
Controlled No
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Estrone-3-sulphate sodium (E3S) is a steroid hormone that is naturally present in the body, specifically in the adrenal gland and ovaries. It is a type of estrogen that plays a vital role in female reproductive health and bone development. E3S is commonly used in clinical settings to treat menopausal symptoms, such as hot flashes and vaginal dryness. It is also used in hormone replacement therapy to help prevent osteoporosis, a condition in which bones become brittle and fragile due to hormonal changes. Chemically, E3S is a sodium salt that is formed from the combination of estrone, a naturally occurring hormone, and sulfate. The sulfate group increases the solubility of E3S in water, making it easier for the body to absorb and utilize. E3S acts as a prodrug, meaning it is converted into estradiol, another type of estrogen, in the body. Estradiol plays a variety of roles in the female reproductive system, including regulating the menstrual cycle and supporting the growth and development of the uterus and breasts. While E3S has many benefits, it is important to note that it can also have side effects. These can include headaches, nausea, and breast tenderness. Additionally, E3S should not be used by individuals with a history of blood clots, liver disease, or breast or uterine cancer. As with any medication, it is important to discuss the potential risks and benefits of E3S with a healthcare provider before beginning treatment.

Related Compounds

Estrone Acetate | Estrone 17-Ethylene Ketal | Estrone-3-Methyl Ether | Estrone 3-O-Sulfamate | Estrone 3-Valerate |

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