Axitinib 13C D3
| Chemical Name | Axitinib 13C D3 |
|---|---|
| Alternate Names | Axitinib Stable Isotopes, Stable Isotopes of Axitinib |
| CAT No. | CS-O-11922 |
| CAS Registry# | 1261432-00-1 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 390.48 g/mol |
| Mol. For. | C₂₁¹³CH₁₅D₃N₄OS |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Axitinib |
| Purity | Not less than 95 % |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | O=C(N[13C]([2H])([2H])[2H])C1=C(C=CC=C1)SC2=CC=C3C(/C=C/C4=CC=CC=N4)=NNC3=C2 |
| Canonical Smiles | CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4 |
| InchIKey | RITAVMQDGBJQJZ-FMIVXFBMSA-N |
| Inchl | InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+ |
| IUPAC | N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide |
| Controlled | No |
| Shipping | Free for purchase above 200$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Axitinib 13C D3 is a stable isotope-labelled version of the cancer drug Axitinib. Axitinib is a small molecule tyrosine kinase inhibitor that is used in the treatment of advanced renal cell carcinoma (RCC), a type of kidney cancer. Axitinib works by blocking the activity of vascular endothelial growth factor (VEGF) receptors, which are involved in the formation of new blood vessels that tumors need to grow and spread.
Axitinib 13C D3 is used in clinical research studies to study the pharmacokinetics and metabolism of Axitinib in the human body. The stable isotopes of carbon and deuterium in Axitinib 13C D3 allow researchers to track the drug's movement and transformation in the body, providing important information about the drug's efficacy and safety.
Chemically, Axitinib 13C D3 has the same molecular formula as Axitinib (C22H18N4OS), but contains three carbon atoms and three deuterium atoms that have been substituted with their stable isotopes. Axitinib 13C D3 is a white to off-white powder that is soluble in organic solvents such as methanol and dimethyl sulfoxide (DMSO).
Overall, Axitinib 13C D3 is a valuable tool for researchers studying the pharmacokinetics and metabolism of Axitinib, and may ultimately lead to the development of more effective and safer cancer treatments.
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Related Compounds
Axitinib-D3 Hydrate | Axitinib D3 |