Bosentan 13C6
| Product Name | Bosentan 13C6 |
|---|---|
| Alternate Names | Bosentan Stable Isotopes, Stable Isotopes of Bosentan |
| CAT No. | CS-O-11952 |
| CAS No. | 147536-97-8(Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 557.57 g/mol |
| Mol. For. | C₂₁[¹³C]₆H₂₉N₅O₆S |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Bosentan |
| Smileys | COC1=C(C=CC=C1)OC(C(N[S](=O)([13C]2=[13CH][13CH]=[13C](C(C)(C)C)[13CH]=[13CH]2)=O)=NC(C3=NC=CC=N3)=N4)=C4OCCO |
| Canonical Smiles | CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC |
| InchIKey | GJPICJJJRGTNOD-UHFFFAOYSA-N |
| Inchl | InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32) |
| IUPAC | 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Bosentan is a medication used to treat pulmonary arterial hypertension (PAH) and is marketed under the brand name Tracleer. Bosentan 13C6 is a stable isotope-labeled form of Bosentan that is used for pharmacokinetic, metabolic, and toxicology studies.
Bosentan is classified as an endothelin receptor antagonist, which means that it blocks the action of endothelin, a peptide hormone that causes constriction of blood vessels and increased blood pressure. By blocking the action of endothelin, Bosentan can dilate blood vessels and reduce the workload on the heart, improving symptoms of PAH.
Bosentan is absorbed rapidly after oral administration and undergoes extensive metabolism in the liver. Bosentan 13C6 is used in studies to determine the metabolic pathways of Bosentan and its metabolites, as well as to quantify the drug in biological samples.
Chemically, Bosentan 13C6 is identical to Bosentan, except that six carbon atoms in the molecule are labeled with the stable isotope carbon-13. This labeling does not change the pharmacological properties of Bosentan, but it allows for more accurate analysis of the drug in biological samples.
Overall, Bosentan 13C6 is an important tool for studying the pharmacokinetics and metabolism of Bosentan, which can lead to a better understanding of how the drug works and how it can be used more effectively in the treatment of PAH.
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Related Compounds
Hydroxy Bosentan D4 | Bosentan 13C2D4 | Bosentan D4 | Hydroxy Bosentan D6 |