Darunavir furan dimer impurity
| Product Name | Darunavir furan dimer impurity |
|---|---|
| Alternate Names | Darunavir Impurities, Impurities of Darunavir |
| CAT No. | CS-O-12035 |
| CAS No. | 1971057-59-6 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 703.80 g/mol |
| Mol. For. | C₃₄H₄₅N₃O₁₁S |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Darunavir |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | O=C(N[C@@H](CC1=CC=CC=C1)[C@H](O)CN(CC(C)C)[S](=O)(C2=CC=C(NC(O[C@@H]3[C@@](CCO4)([H])[C@@]4([H])OC3)=O)C=C2)=O)O[C@@H]5[C@@](CCO6)([H])[C@@]6([H])OC5 |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Darunavir is a widely used antiretroviral drug for the treatment of HIV-1 infection. However, during the manufacturing process of Darunavir, a small amount of impurity called Darunavir furan dimer may be formed. This impurity has been found to have a potential impact on the efficacy and safety of the drug. Therefore, it is important to understand the chemical information and usage of Darunavir furan dimer impurity.
Darunavir furan dimer is a chemical compound that is formed as a result of the reaction between two molecules of Darunavir via a furan ring. It has been identified as a potential genotoxic impurity, which means it has the potential to damage DNA and cause mutations. This can lead to serious health risks and thus, it is essential to limit the presence of this impurity in Darunavir.
The usage of Darunavir furan dimer impurity is limited to its identification, characterization, and quantification during the manufacturing process of Darunavir. Several analytical techniques have been developed to detect and quantify the impurity, including High-Performance Liquid Chromatography (HPLC) and Gas Chromatography-Mass Spectrometry (GC-MS).
In conclusion, Darunavir furan dimer impurity is a potential genotoxic impurity that needs to be carefully monitored and limited during the manufacturing process of Darunavir. Its chemical information and usage are important to ensure the safety and efficacy of the drug.
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Related Compounds
Darunavir Impurity 46 | Darunavir impurity B | Darunavir Impurity 38 | Darunavir Impurity 7 (S,S-Isomer) | Darunavir Isomer 2 | Darunavir Urea impurity | Darunavir СВZ urea impurity | Darunavir Impurity 11 | Darunavir Impurity A Enantiomer | Darunavir Difuranyl impurity | Darunavir Impurity 10 | Darunavir Impurity 8 (R,R-Isomer) | N-[3S-benzyloxycarbonylamino-2R-hydroxy-4-phenyl]-N-isobutylamine | Darunavir СВZ amino impurity | Darunavir Impurity 16 | Darunavir N-methyl urea impurity | Darunavir Impurity D | Darunavir Diamino impurity | Darunavir Nitro complex impurity | Darunavir Isomer 1 | Darunavir СВZ furan impurity | Darunavir Amine dimer impurity | Darunavir Impurity 23 | Darunavir Carbamic Acid Methyl Ester |