Darunavir СВZ urea impurity
| Product Name | Darunavir СВZ urea impurity |
|---|---|
| Alternate Names | Darunavir Impurities, Impurities of Darunavir |
| CAT No. | CS-O-12075 |
| CAS No. | Not Available |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 942.40 g/mol |
| Mol. For. | C₄₉H₆₂N₆O₉S₂ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Darunavir |
| Purity | 95% |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | O=C(OCC1=CC=CC=C1)N[C@H]([C@H](O)CN(CC(C)C)S(=O)(C2=CC=C(NC(N[C@H]([C@H](O)CN(CC(C)C)S(=O)(C3=CC=C(N)C=C3)=O)CC4=CC=CC=C4)=O)C=C2)=O)CC5=CC=CC=C5 |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Darunavir is a protease inhibitor used for the treatment of human immunodeficiency virus (HIV) infection. It works by preventing the replication of the virus and reducing the viral load in the body. However, during the manufacturing process of Darunavir, a urea impurity called Darunavir СВZ is formed. This impurity has been identified as a potential carcinogen and is therefore regulated by various health and safety agencies.
Darunavir СВZ is a white crystalline powder with a molecular weight of 320.39 g/mol. Its chemical formula is C15H16N2O3 and it has a melting point of 214-216°C. The impurity is formed due to the reaction between Darunavir and the solvents used during the manufacturing process. It is important to note that Darunavir СВZ does not have any therapeutic benefits and is considered a contaminant.
To ensure the safety and efficacy of Darunavir, regulatory agencies have set limits on the amount of Darunavir СВZ that can be present in the drug. The United States Food and Drug Administration (FDA), for example, has set a limit of 0.2% for the impurity. Manufacturers must therefore ensure that the levels of Darunavir СВZ in their Darunavir products are below these permissible limits before they can be sold and used for the treatment of HIV.
Get an Instant Quote
Related Compounds
Darunavir Urea impurity | N-[3S-benzyloxycarbonylamino-2R-hydroxy-4-phenyl]-N-isobutylamine | Darunavir Impurity 10 | Darunavir Impurity 7 (S,S-Isomer) | Darunavir Impurity 23 | Darunavir Nitro complex impurity | Darunavir N-methyl urea impurity | Darunavir Impurity 38 | Darunavir Diamino impurity | Darunavir Isomer 2 | Darunavir furan dimer impurity | Darunavir Amine dimer impurity | Darunavir Impurity 11 | Darunavir Impurity D | Darunavir Impurity A Enantiomer | Darunavir Isomer 1 | Darunavir Carbamic Acid Methyl Ester | Darunavir impurity B | Darunavir СВZ furan impurity | Darunavir Impurity 16 | Darunavir СВZ amino impurity | Darunavir Impurity 8 (R,R-Isomer) | Darunavir Difuranyl impurity | Darunavir Impurity 46 |