Tolterodine Monomer

Tolterodine Monomer is a medication used to treat symptoms of an overactive bladder, such as frequent urination, urgency, and incontinence. It works by relaxing the bladder muscles, allowing for greater control over urination. Tolterodine Monomer is available in both immediate-release and extended-release formulations, with the extended-release version being taken once a day for convenience. The chemical structure of Tolterodine Monomer consists of a quinuclidine core with a substituted benzene ring. It is a competitive antagonist of the muscarinic acetylcholine receptor, which is responsible for bladder contractions. Tolterodine Monomer binds to the receptor, preventing acetylcholine from acting on it and thereby reducing bladder contractions. Tolterodine Monomer is metabolized in the liver and excreted through the kidneys. Its elimination half-life is approximately 2 to 3 hours. The medication is contraindicated in patients with urinary retention, gastric retention, or uncontrolled narrow-angle glaucoma. Side effects of Tolterodine Monomer include dry mouth, constipation, blurred vision, and dizziness. In rare cases, it can cause an allergic reaction, which may manifest as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. Overall, Tolterodine Monomer is a useful medication for managing symptoms of an overactive bladder. It should be used under the guidance of a healthcare professional and with caution in patients with certain medical conditions.