19-Hydroxy-10-deacetyl Baccatin-III

Product Name 19-Hydroxy-10-deacetyl Baccatin-III
CAT No. CS-O-13582
CAS No. 154083-99-5
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Therapeutic Anti-Cancer / Oncology
Smileys CC(O[C@]([C@@]1([H])C[C@@H]2O)(CO1)[C@]([C@@H]([C@]3(C(C)(C)C4=C(C)[C@@H](O)C3)O)OC(C5=CC=CC=C5)=O)([H])[C@@]2(C([C@@H]4O)=O)CO)=O
Canonical Smiles CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1=O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)CO)O
InchIKey HALOPRXVBVZSAC-RIFKXWPOSA-N
Inchl InChI=1S/C29H34O11/c1-14-17(32)11-29(37)24(39-25(36)16-8-6-5-7-9-16)22-27(12-30,23(35)21(34)20(14)26(29,3)4)18(33)10-19-28(22,13-38-19)40-15(2)31/h5-9,18-19,21-22,24,30,33-34,37H,10-13H2,1-4H3/t18-,19+,21+,22-,24-,27+,28-,29+/m0/s1
IUPAC [(1S,2S,3R,4S,7R,9S,10R,12R)-4-acetyloxy-1,9,12-trihydroxy-10-(hydroxymethyl)-14,17,17-trimethyl-11,15-dioxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Controlled No
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19-Hydroxy-10-deacetyl Baccatin-III is a natural organic compound derived from the needles of the Pacific yew tree (Taxus brevifolia). It is a precursor to the widely used chemotherapy drug Paclitaxel, which is commonly used to treat various types of cancer, including ovarian, breast, and lung cancer. The chemical formula for 19-Hydroxy-10-deacetyl Baccatin-III is C29H36O10 and it has a molecular weight of 544.59 g/mol. The compound is a white to off-white powder and is soluble in methanol, ethanol, and dichloromethane. 19-Hydroxy-10-deacetyl Baccatin-III is often used in the pharmaceutical industry as a starting material for the synthesis of Paclitaxel. It is converted into Paclitaxel through a series of chemical reactions, including acetylation and reduction. Paclitaxel is a potent anticancer drug that works by preventing cancer cells from dividing and growing. In addition to its use in the pharmaceutical industry, 19-Hydroxy-10-deacetyl Baccatin-III has also been studied for its potential as an insecticide and as a treatment for Alzheimer's disease. Research has shown that the compound may have neuroprotective properties and could potentially be used to prevent or treat neurodegenerative diseases. Overall, 19-Hydroxy-10-deacetyl Baccatin-III is a valuable compound with a wide range of potential uses in the pharmaceutical and agricultural industries, as well as in medical research.

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