12-Hydroxy Nevirapine D4

Product Name 12-Hydroxy Nevirapine D4
Alternate Names Nevirapine Stable Isotopes, Stable Isotopes of Nevirapine
CAT No. CS-O-13658
CAS No. 133627-24-4 (Unlabeled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Nevirapine
Therapeutic Antiretroviral / Anti-HIV
Smileys OCC1=CC=NC(N(C2C([2H])([2H])C2([2H])[2H])C3=NC=CC=C43)=C1NC4=O
Canonical Smiles C1CC1N2C3=C(C=CC=N3)C(=O)NC4=C(C=CN=C42)CO
InchIKey SEBABOMFNCVZGF-UHFFFAOYSA-N
Inchl InChI=1S/C15H14N4O2/c20-8-9-5-7-17-14-12(9)18-15(21)11-2-1-6-16-13(11)19(14)10-3-4-10/h1-2,5-7,10,20H,3-4,8H2,(H,18,21)
IUPAC 2-cyclopropyl-7-(hydroxymethyl)-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
Controlled No
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12-Hydroxy Nevirapine D4 is a derivative of Nevirapine, which is an antiretroviral drug used for the treatment of HIV/AIDS. 12-Hydroxy Nevirapine D4 is a stable isotope-labeled compound that is used in pharmacokinetic studies to determine the metabolic fate of Nevirapine in the human body. The chemical formula of 12-Hydroxy Nevirapine D4 is C15H8D4N4O2, and it has a molecular weight of 296.35 g/mol. The compound is synthesized using deuterium oxide as a solvent and deuterated reagents. The usage of 12-Hydroxy Nevirapine D4 is mainly in drug metabolism studies, where it is used as an internal standard for liquid chromatography-mass spectrometry (LC-MS) analysis. This stable isotope-labeled compound helps in accurately quantifying the levels of Nevirapine and its metabolites in biological samples, such as blood, urine, and tissues. The chemical information of 12-Hydroxy Nevirapine D4 reveals that it is a potent inhibitor of HIV reverse transcriptase, which is the enzyme responsible for the replication of the virus. The compound works by binding to the enzyme, blocking its activity and preventing the virus from multiplying. In conclusion, 12-Hydroxy Nevirapine D4 is an essential tool for drug metabolism studies and provides valuable insights into the pharmacokinetics of Nevirapine in the human body. Its chemical properties and inhibitory effects on HIV reverse transcriptase make it an important compound in the fight against HIV/AIDS.

Related Compounds

Nevirapine D3 | Nevirapine D8 | Nevirapine D4 | Nevirapine-D4 | Nevirapine D5 |

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