8-Hydroxy-Efavirenz D4

Product Name 8-Hydroxy-Efavirenz D4
Alternate Names Efavirenz Stable Isotopes, Stable Isotopes of Efavirenz
CAT No. CS-O-13659
CAS No. 205754-33-2(Unlabeled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Efavirenz
Therapeutic Antiretroviral / Anti-HIV
Smileys FC(F)(F)[C@](C1=CC(Cl)=CC(O)=C1NC2=O)(O2)C#CC3C([2H])([2H])C3([2H])[2H]
Canonical Smiles C1CC1C#CC2(C3=C(C(=CC(=C3)Cl)O)NC(=O)O2)C(F)(F)F
InchIKey OOVOMPCQLMFEDT-ZDUSSCGKSA-N
Inchl InChI=1S/C14H9ClF3NO3/c15-8-5-9-11(10(20)6-8)19-12(21)22-13(9,14(16,17)18)4-3-7-1-2-7/h5-7,20H,1-2H2,(H,19,21)/t13-/m0/s1
IUPAC (4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Controlled No
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8-Hydroxy-Efavirenz D4 is a stable isotope-labeled analog of the antiretroviral drug Efavirenz. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that is commonly used in the treatment of HIV-1 infection. This medication works by inhibiting the activity of reverse transcriptase, an enzyme that is essential for the replication of HIV-1. The addition of deuterium atoms to certain positions within the molecular structure of 8-Hydroxy-Efavirenz D4 allows for its use in research and drug development studies. This compound is useful for pharmacokinetic studies, as it can be used as a stable isotope internal standard for the quantification of Efavirenz in biological samples. 8-Hydroxy-Efavirenz D4 has a molecular formula of C14H6D4ClF3NO2 and a molecular weight of 329.73 g/mol. It is a white to off-white powder that is soluble in organic solvents such as methanol, ethanol, and DMSO. In terms of safety, 8-Hydroxy-Efavirenz D4 should be handled with care and in accordance with appropriate safety protocols. It should be stored in a cool, dry place and protected from light. As with all chemicals, it should only be used by trained personnel in a properly equipped laboratory.

Related Compounds

Efavirenz D5 | rac Efavirenz D4 | rac 8,14-Dihydroxy Efavirenz-d4 | Efavirenz 13C6 | rac 7-Hydroxy Efavirenz-d4 (Major) |

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