Ledipasvir D8

Product Name Ledipasvir D8
Alternate Names Ledipasvir Stable Isotopes, Stable Isotopes of Ledipasvir
CAT No. CS-O-13774
CAS No. 1256388-51-8(Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 897.05 g/mol
Mol. For. C49H46D8F2N8O6
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ledipasvir
Purity 95%
Therapeutic Antiretroviral / Anti-HIV
Smileys O=C(N1CC2(CC2)C[C@H]1C3=NC=C(C4=CC=C(C5=CC=C(C6=CC=C7C(NC([C@H]([C@@H]8C[C@H]9CC8)N9C(C(C(C)C)NC(OC)=O)=O)=N7)=C6)C=C%105)C(C%10(F)F)=C4)N3)C(C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])([2H])NC(OC)=O
Canonical Smiles CC(C)C(C(=O)N1CC2(CC2)CC1C3=NC=C(N3)C4=CC5=C(C=C4)C6=C(C5(F)F)C=C(C=C6)C7=CC8=C(C=C7)N=C(N8)C9C1CCC(C1)N9C(=O)C(C(C)C)NC(=O)OC)NC(=O)OC
InchIKey VRTWBAAJJOHBQU-KMWAZVGDSA-N
Inchl InChI=1S/C49H54F2N8O6/c1-24(2)39(56-46(62)64-5)44(60)58-23-48(15-16-48)21-38(58)42-52-22-37(55-42)28-9-13-32-31-12-8-26(18-33(31)49(50,51)34(32)19-28)27-10-14-35-36(20-27)54-43(53-35)41-29-7-11-30(17-29)59(41)45(61)40(25(3)4)57-47(63)65-6/h8-10,12-14,18-20,22,24-25,29-30,38-41H,7,11,15-17,21,23H2,1-6H3,(H,52,55)(H,53,54)(H,56,62)(H,57,63)/t29-,30+,38-,39-,40-,41-/m0/s1
IUPAC methyl N-[(2S)-1-[(6S)-6-[5-[9,9-difluoro-7-[2-[(1R,3S,4S)-2-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-2-azabicyclo[2.2.1]heptan-3-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate
Controlled No
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Ledipasvir D8 is a deuterated form of Ledipasvir, a potent inhibitor of the NS5A protein of the hepatitis C virus. It is a highly effective drug that is used in combination with other antiviral agents to treat chronic hepatitis C virus infections. Ledipasvir D8 is commonly used in the form of a tablet, and it is taken orally once a day. The chemical structure of Ledipasvir D8 contains eight deuterium atoms, which are stable isotopes of hydrogen. This makes Ledipasvir D8 more stable and less likely to undergo metabolic breakdown, resulting in a longer half-life compared to Ledipasvir. It is also less likely to be affected by drug-drug interactions, making it a more reliable drug for the treatment of hepatitis C. Ledipasvir D8 works by inhibiting the NS5A protein, which is essential for the replication of the hepatitis C virus. This prevents the virus from multiplying and spreading in the body, leading to the eventual clearance of the virus. In conclusion, Ledipasvir D8 is a highly effective antiviral drug used in the treatment of chronic hepatitis C virus infections. Its stability and resistance to drug-drug interactions make it a reliable drug for the successful treatment of this disease.

Related Compounds

Ledipasvir D6 | Ledipasvir 13C2 D6 | Ledipasvir D16 |

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