Azacitidine Related compound C(Isomer-1)

Chemical Name Azacitidine Related compound C(Isomer-1)
Alternate Names Azacitidine Impurities, Impurities of Azacitidine
CAT No. CS-O-13991
CAS Registry# 4336-46-3
Category Impurities
Stock IN-Stock
Mol. Wt. 463.31 g/mol
Mol. For. C13H17N7O12
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Azacitidine
Therapeutic Anti-Cancer / Oncology
Smileys O=[N+](C(C=C([N+]([O-])=O)C=C1[N+]([O-])=O)=C1O)[O-].O=C(NC(N)=N)N[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
Canonical Smiles C1=C(C=C(C(=C1[N+](=O)[O-])O)[N+](=O)[O-])[N+](=O)[O-].C(C1C(C(C(O1)NC(=O)N=C(N)N)O)O)O
InchIKey RTONSOUBEUPEOS-QLRMNKGWSA-N
Inchl InChI=1S/C7H14N4O5.C6H3N3O7/c8-6(9)11-7(15)10-5-4(14)3(13)2(1-12)16-5;10-6-4(8(13)14)1-3(7(11)12)2-5(6)9(15)16/h2-5,12-14H,1H2,(H5,8,9,10,11,15);1-2,10H/t2-,3-,4-,5-;/m1./s1
IUPAC 1-(diaminomethylidene)-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea;2,4,6-trinitrophenol
Controlled No
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Azacitidine Related compound C (Isomer-1) is a synthetic nucleoside analog that is used in the treatment of various types of cancers, including myelodysplastic syndrome and acute myeloid leukemia. It is a structural isomer of Azacitidine, which is a drug that is approved by the FDA for the same indication. Azacitidine Related compound C (Isomer-1) is not an approved drug, but it is used as a reference standard in various analytical methods to determine the purity and potency of Azacitidine. The chemical name of Azacitidine Related compound C (Isomer-1) is 4-Amino-1-(β-D-ribofuranosyl)-2(1H)-pyrimidinone. It has a molecular formula of C9H13N3O4 and a molecular weight of 227.22 g/mol. The compound is a white to off-white powder that is soluble in water and methanol. In terms of its mechanism of action, Azacitidine Related compound C (Isomer-1) is believed to work by inhibiting DNA methyltransferases, which are enzymes that add methyl groups to DNA. By inhibiting these enzymes, Azacitidine Related compound C (Isomer-1) can help to restore normal gene expression patterns, which may be disrupted in cancer cells. Overall, Azacitidine Related compound C (Isomer-1) is an important reference standard in the field of cancer research and drug development. Its chemical properties and mechanism of action make it a valuable tool for understanding the pharmacology of nucleoside analogs and their potential therapeutic applications.

Related Compounds

Azacitidine Impurity C isomers | Azacitidine Impurity 7 | Azacitidine Impurity C isomers 2 | Beta-L-Ribofuranose | Azacitidine impurity 48 | Azacitidine Impurity 24 | Tri Acetyl Azacitidine | Azacitidine Impurity C isomers 4 | Azacitidine Impurity | Azacitidine Impurity 1 | N-(Diaminoethylene)-N'-(β-D-ribofuranosyl)-carbamimidic Acid | Azacitidine Amine Isomer-4 | Azacitidine Amine Impurity | Azacitidine Impurity 6 | Azacitidine Impurity C isomers 2(Free Base) | Monoacyl Azacitidine | Azacitidine Impurity 4 | Azacitidine Impurity 9 | Azacitidine Impurity 12 | Azacitidine Impurity C isomers 3 | Azacitidine Related Compound B | Azacitidine Impurity 23 | Azacitidine Impurity 15 | Azacitidine N- Formyl Impurity | Azacitidine Impurity 16 | Azacitidine Impurity 14 | Azacitidine Related Compound -C Isomer -3 |

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