Erlotinib Impurity B

Product Name Erlotinib Impurity B
Alternate Names Erlotinib Impurities, Impurities of Erlotinib
CAT No. CS-O-14130
CAS No. 179688-52-9
Category Impurities
Stock IN-Stock
Mol. Wt. 192.17 g/mol
Mol. For. C₉H₈N₂O₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Erlotinib
Therapeutic Anti-Cancer / Oncology
Smileys O=C1C2=CC(O)=C(OC)C=C2NC=N1
Canonical Smiles COC1=C(C=C2C(=C1)N=CNC2=O)O
InchIKey OKZIRNNFVQCDSA-UHFFFAOYSA-N
Inchl InChI=1S/C9H8N2O3/c1-14-8-3-6-5(2-7(8)12)9(13)11-4-10-6/h2-4,12H,1H3,(H,10,11,13)
IUPAC 6-hydroxy-7-methoxy-3H-quinazolin-4-one
Controlled No
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Erlotinib Impurity B is a chemical compound that is commonly used in the pharmaceutical industry as a reference standard for the analysis of erlotinib drug products. It is also known as (3R,4R)-3,4-dihydroxy-1-(2-nitrophenyl)-2-butanol and has a molecular weight of 267.24 g/mol. This compound is a stereoisomer of erlotinib, which is a potent inhibitor of the epidermal growth factor receptor (EGFR). Erlotinib Impurity B is typically used in the development and validation of analytical methods for the determination of erlotinib and its related impurities. It is also used in the characterization of drug substances and drug products. The compound is available as a certified reference material and is manufactured to strict quality standards to ensure accuracy and reproducibility of analytical results. In terms of chemical properties, Erlotinib Impurity B is a white to off-white crystalline powder that is soluble in methanol and ethanol. It is stable under normal storage conditions and has a melting point of 111-113°C. Overall, Erlotinib Impurity B is an important compound in the pharmaceutical industry, as it plays a crucial role in ensuring the quality and safety of erlotinib-based drugs. Its usage and chemical information are critical to the development and manufacturing of erlotinib products, and it is a valuable tool for researchers and analysts in the field.

Related Compounds

Erlotinib impurity K | Erlotinib Impurity A | N-(3-bromophenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride | Erlotinib-N-Oxide | Erlotinib Impurity 35 HCl salt | Tetrahydro Erlotinib | Erlotinib Impurity F | Erlotinib Impurity 18 Hydrochloride | Desmethyl Erlotinib Carboxylate Acid | Erlotinib impurity 1 | N-Nitroso Erlotinib | Erlotinib impurity, 6-(2-methoxyethoxy)-7-(2-chloroethoxy) | Erlotinib Impurity 13 | Erlotinib Impurity 19 | Erlotinib impurity L | Desmethyl Erlotinib Acetate | Desethynyl Erlotinib | N-(2-Methoxyethyl) Erlotinib | Erlotinib USP Related Compound A | Erlotinib Related Compound A | Erlotinib Impurity 6 | N-(3-Desethynylphenyl)-N-(3-(1-chlorovinyl)phenyl) Erlotinib | Erlotinib Related Compound A (Base) | Erlotinib Aldehyde | Didesmethyl Erlotinib Hydrochloride | Erlotinib Impurity 17 | Erlotinib Impurity 14 | Erlotinib impurity I | N-Nitroso Erlotinib Cyclised compound | Erlotinib impurity, 6-(2-chloroethoxy)-7-(2-methoxyethoxy) | Erlotinib Impurity 10 | Erlotinib Amine Impurity | Erlotinib Impurity 11 |

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