4β-Hydroxycholesterol D4
| Product Name | 4β-Hydroxycholesterol D4 |
|---|---|
| Alternate Names | Cholesterol Stable Isotopes, Stable Isotopes of Cholesterol |
| CAT No. | CS-O-14358 |
| CAS No. | 1363529-44-5 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 406.68 g/mol |
| Mol. For. | C₂₇H₄₂D₄O₂ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Cholesterol |
| Purity | Not less than 90 % |
| Smileys | C[C@@](C1=CC2)(CC[C@H](O)[C@@H]1O)[C@]3([H])[C@]2([H])[C@@](CC[C@]4([H])[C@H](C)CCCC(C)([2H])C([2H])([2H])[2H])([H])[C@]4(C)CC3 |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
4β-Hydroxycholesterol D4, also known as 4β-Hydroxycholesterol-26,26,26,27,27,27-d6, is a stable isotopic labeled form of 4β-Hydroxycholesterol. It is a cholesterol metabolite that plays an important role in cholesterol biosynthesis. It is formed by the hydroxylation of cholesterol at the 4β position by CYP3A4, an important enzyme present in the liver. 4β-Hydroxycholesterol D4 is used as a biomarker in clinical research to evaluate CYP3A4 activity in humans.
Chemically, 4β-Hydroxycholesterol D4 has a molecular formula of C27H41D6O2 and a molecular weight of 429.76 g/mol. It is a white to off-white powder that is stable under normal storage conditions. It is soluble in organic solvents like methanol, ethanol, and dimethyl sulfoxide (DMSO).
In terms of usage, 4β-Hydroxycholesterol D4 is primarily used in research studies to understand the role of CYP3A4 in cholesterol metabolism and drug metabolism. It is also used as an internal standard in LC-MS/MS methods for the quantification of 4β-Hydroxycholesterol levels in biological samples. Additionally, it can be used in the development of new drugs that target cholesterol metabolism and CYP3A4 activity.
In conclusion, 4β-Hydroxycholesterol D4 is a stable isotopic labeled form of 4β-Hydroxycholesterol that plays a significant role in cholesterol biosynthesis and drug metabolism. It is primarily used in clinical research to evaluate CYP3A4 activity in humans, as well as in LC-MS/MS methods for the quantification of 4β-Hydroxycholesterol levels in biological samples.
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Related Compounds
Cholesterol-13C5 | Cholesterol-d7 | Cholesterol-d4 | CHOLESTEROL 13C2 | Cholesterol-[2,2,3,4,4,6-d6] (Solution) | Cholesterol-26,26,26,27,27,27-D6 | Cholesterol-[2,3,4-13C3] | Cholesterol-[2,3,4-13C3] (Solution) | CHOLESTEROL-3-OCTANOATE OCTANOATE-13C | Cholesterol 3-Acetate-d7 |