Sunitinib Impurity I

Product Name Sunitinib Impurity I
Alternate Names Sunitinib Impurities, Impurities of Sunitinib
CAT No. CS-O-14530
CAS No. 1186651-51-3
Category Impurities
Stock IN-Stock
Mol. Wt. 299.30 g/mol
Mol. For. C₁₆H₁₄FN₃O₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Sunitinib
Therapeutic Anti-Cancer / Oncology
Smileys O=C1/C(C2=CC(F)=CC=C2N1)=C\C(NC(C)=C3C(N)=O)=C3C
Canonical Smiles CC1=C(NC(=C1C(=O)N)C)C=C2C3=C(C=CC(=C3)F)NC2=O
InchIKey WAHDFFHPBSCPOQ-WDZFZDKYSA-N
Inchl InChI=1S/C16H14FN3O2/c1-7-13(19-8(2)14(7)15(18)21)6-11-10-5-9(17)3-4-12(10)20-16(11)22/h3-6,19H,1-2H3,(H2,18,21)(H,20,22)/b11-6-
IUPAC 5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Controlled No
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Sunitinib Impurity I is a chemical compound that is used in the pharmaceutical industry as a reference standard for the analysis of sunitinib malate, a tyrosine kinase inhibitor drug used to treat cancer. The impurity is a byproduct of the synthesis of sunitinib malate and can be present in trace amounts in the drug product. Sunitinib Impurity I has a chemical formula of C21H16ClN3O2 and a molecular weight of 375.83 g/mol. It is a yellow solid with a melting point range of 126-129°C. The compound is soluble in organic solvents such as DMSO, methanol, and acetonitrile. Chemically, Sunitinib Impurity I is a derivative of the parent compound sunitinib, with a chlorine atom substituted for a methyl group. The compound has been characterized using various analytical techniques such as nuclear magnetic resonance spectroscopy, mass spectrometry, and infrared spectroscopy. In the pharmaceutical industry, Sunitinib Impurity I is used as a reference standard for the analysis of sunitinib malate. It is used to verify the purity of the drug substance and to ensure that the drug product meets regulatory requirements for quality and safety. The impurity can also be used in the development of analytical methods for the analysis of sunitinib malate.

Related Compounds

Sunitinib Ketone Impurity | Sunitinib N-3-(Dimethylamino)propyl impurity | N-Desethyl Sunitinib | Sunitinib Impurity C | Sunitinib Impurity 10 | Sunitinib Impurity 8 | N-Desethylsunitinib-d4 TFA Salt | N-Desethyl N-Nitroso Sunitinib impurity | Sunitinib Impurity 1 | Sunitinib Carboxylic Acid | Sunitinib Impurity 18 | N-Boc-N,N-didesethyl Sunitinib | Sunitinib Impurity II (SNT 700) | sunitinib Impurity B | Sunitinib Impurity 7 | Sunitinib formyl impurity | N-Desethylsunitinib TFA Salt | Sunitinib Impurity H |

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