Loratadine EP Impurity F

Loratadine EP Impurity F is a chemical compound that is commonly used as a reference standard for the analysis and characterization of Loratadine, an antihistamine drug used to treat allergic reactions. This impurity is a derivative of Loratadine and belongs to the class of organic compounds known as piperidines. It is a white to off-white powder that has a molecular weight of 365.54 g/mol. Loratadine EP Impurity F is primarily used in quality control and analytical laboratories to ensure the purity and potency of Loratadine formulations. The impurity is also used as a standard in pharmacological research to investigate the pharmacokinetics and metabolism of Loratadine in the body. Additionally, it is used in the development and validation of analytical methods for quantifying Loratadine and its related substances in pharmaceuticals. The chemical name of Loratadine EP Impurity F is ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate. It has a melting point range of 137-141°C and a purity of greater than 98%. The impurity is stable under normal storage conditions and is typically stored in a cool, dry place away from direct sunlight. In summary, Loratadine EP Impurity F is a useful reference standard for the analysis and characterization of Loratadine in pharmaceutical formulations. Its chemical properties and stability make it an important tool for quality control and analytical laboratories, as well as pharmacological research.