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β-Gemcitabine 13C,15N2 Hydrochloride

Chemical Name β-Gemcitabine 13C,15N2 Hydrochloride
CAT No. CS-O-14759
CAS Registry# 1233921-74-8 (Freebase)
Status Prompt Dispatch
Category Stable Isotopes
Mol. Wt. 302.64 g/mol
Mol. For. C₈¹³CH₁₂ClF₂N¹⁵N₂O₄
Hazardous This is a Hazardous Compound
COA View Sample COA

Additional Information

Controlled No
Parent API Gemcitabine
Purity >98%
Therapeutic Immunosuppressants
Smileys FC1([C@@H]([15N](C=CC(N)=[15N]2)[13C]2=O)O[C@H](CO)[C@H]1O)F.Cl
Hazardous Yes

Usage and description

β-Gemcitabine 13C,15N2 Hydrochloride is a modified version of the drug Gemcitabine, which is commonly used to treat various types of cancer. The addition of carbon-13 and nitrogen-15 isotopes to the compound allows for more precise tracking and analysis of its distribution and metabolism within the body. This enables researchers to gain a better understanding of how the drug is working, and potentially identify ways to optimize its effectiveness. Chemically, β-Gemcitabine 13C,15N2 Hydrochloride is a nucleoside analogue, meaning it mimics the structure of the nucleosides that make up DNA. When the drug is taken up by cancer cells, it is incorporated into their DNA, disrupting their ability to divide and ultimately leading to cell death. This mechanism of action makes it particularly effective against rapidly dividing cancer cells. The drug is typically administered intravenously, and the dose and frequency of treatment will depend on the type and stage of cancer being treated, as well as the patient's overall health. Common side effects of β-Gemcitabine 13C,15N2 Hydrochloride include nausea, vomiting, fatigue, and decreased white blood cell count. As with all medications, it is important to follow the prescribed dosing instructions and to consult with a healthcare professional if any concerning side effects arise.

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