Ketorolac EP Impurity H

Ketorolac EP Impurity H, also known as 5-Bromo-2-methoxybenzoic acid, is a chemical compound that is widely used in the pharmaceutical industry as a reference standard for the analysis of Ketorolac, a nonsteroidal anti-inflammatory drug. As an impurity of Ketorolac, it is important to have a precise and accurate measurement of its concentration in pharmaceutical formulations as it can affect the efficacy, safety, and stability of the drug product. The presence of higher levels of Ketorolac EP Impurity H can lead to adverse effects such as gastrointestinal bleeding, ulcers, and renal dysfunction. Therefore, it is essential to monitor the levels of this impurity during the manufacturing process and batch release of Ketorolac. Chemically, Ketorolac EP Impurity H is a white crystalline powder with a molecular weight of 241.02 g/mol and a melting point of 177-181°C. It belongs to the family of benzoic acids and is a derivative of 2-methoxybenzoic acid. Its chemical structure contains a bromine atom attached to the benzene ring which imparts unique properties and reactivity to the compound. In conclusion, Ketorolac EP Impurity H is an important reference standard for the analysis of Ketorolac in pharmaceutical formulations. Its precise measurement and control are critical for ensuring the quality, safety, and efficacy of the drug product.