7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione
| Product Name | 7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione |
|---|---|
| Alternate Names | Linagliptin Impurities, Impurities of Linagliptin |
| CAT No. | CS-O-14821 |
| CAS No. | 586408-08-4 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 218.21 g/mol |
| Mol. For. | C₁₀H₁₀N₄O₂ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Linagliptin |
| Purity | >98% |
| Therapeutic | Anti-Diabetic |
| Smileys | CC#CCN1C(C(NC2=O)=O)=C(N2C)N=C1 |
| Canonical Smiles | CC#CCN1C=NC2=C1C(=O)NC(=O)N2C |
| InchIKey | CPLWLMDNRLTZHK-UHFFFAOYSA-N |
| Inchl | InChI=1S/C10H10N4O2/c1-3-4-5-14-6-11-8-7(14)9(15)12-10(16)13(8)2/h6H,5H2,1-2H3,(H,12,15,16) |
| IUPAC | 7-but-2-ynyl-3-methylpurine-2,6-dione |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione is a chemical compound with the molecular formula C12H10N4O2. It is also known as BU-224 and is a potent inhibitor of the enzyme phosphodiesterase 4 (PDE4). PDE4 inhibitors have been shown to have therapeutic potential in a range of conditions such as asthma, chronic obstructive pulmonary disease (COPD), and inflammatory bowel disease (IBD).
The compound's structure consists of a purine ring with a but-2-yn-1-yl group attached at the 7 position and a methyl group at the 3 position. The purine ring is a bicyclic structure composed of a pyrimidine ring fused with an imidazole ring. The compound's melting point is 243-244°C, and it has a molecular weight of 234.23 g/mol.
In terms of usage, 7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione is primarily used as a research chemical to investigate the role of PDE4 inhibition in various disease states. It is not currently approved for clinical use in humans. However, preclinical studies have shown promising results, and further research is underway to determine its potential as a therapeutic agent.
In conclusion, 7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione is a potent PDE4 inhibitor with potential therapeutic applications in various disease states. Its chemical structure and properties make it a valuable tool for research in this area. However, its clinical use in humans is yet to be determined.
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Related Compounds
Linagliptin Ethyldimer | Desbutyl N-nitroso Linagliptin Impurity 52 | Linagliptin Impurity 2 | Linagliptin impurity P | Linagliptin Impurity 41 | Linagliptin impurity U | Linagliptin tert-butyl carbamate | Linagliptin Impurity I | N-nitroso Linagliptin Impurity C | Linagliptin Impurity-VII | Linagliptin-4-methylquinazolin-2-yl-methyl dimer | Linagliptin Impurity 5 | Linagliptin Dimer Impurity 4 | Linagliptin impurity O | Linagliptin Impurity 25 | Linagliptin impurity 115 | Linagliptin impurity J | Linagliptin impurity Y | Bromobutene Linagliptin impurity VII | Linagliptin Impurity 29 | Linagliptin Impurity N | Linagliptin Impurity 36 | Linagliptin impurity E | Linagliptin Impurity 42 | Linagliptin Impurity 3 | N-Hydroxy Linagliptin | Linagliptin Impurity II | Linagliptin Dimer Impurity | Linagliptin Dimer Impurity | Linagliptin Impurity 30 | Linagliptin Impurity T | Linagliptin Impurity D | Linagliptin N-Amino Acyl Impurity | Linagliptin Impurity 38 | Linagliptin impurity R | Linagliptin impurity B | Linagliptin impurity K | Linagliptin Diene Impurity | Linagliptin Impurity 75 HCl salt | Linagliptin Impurity 51 | Linagliptin impurity F | N-Phthalimide-linagliptin | Linagliptin Impurity Q | Linagliptin impurity S | Linagliptin impurity C | Linagliptin Pentahydroxy Impurity | N-Formyl Linagliptin | Linagliptin Glycosamine | Linagliptin Impurity 106 | Desalkyl N-nitroso Linagliptin | Linagliptin impurity V | Linagliptin impurity M | N-nitroso linagliptin impurity 92 | Linagliptin Methyldimer | N-(6-Amino-1,2,3,4-tetrahydro-1-methyl-2,4-dioxo-5-pyrimidinyl)formamide | Linagliptin Impurity 43 | Linagliptin impurity X | Desbutyl N-nitroso Linagliptin impurity 16 | Linagliptin Impurity 1 | Linagliptin impurity H | Linagliptin Impurity 9 | Linagliptin Hydroxy Impurity | Linagliptin Impurity 17 | Linagliptin Impurity 49 | Linagliptin Impurity 35 | Hydroxy Methyl Linagliptin | Linagliptin-d9 | Linagliptin Impurity W | Linagliptin Dimer impurity (N-C-C-C Dimer) | Linagliptin Impurity 76 TrisHCl salt |