Macitentan ACT-373898
| Product Name | Macitentan ACT-373898 |
|---|---|
| Alternate Names | Macitentan Impurities, Impurities of Macitentan |
| CAT No. | CS-O-14882 |
| CAS No. | 1433875-14-9 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 445.29 g/mol |
| Mol. For. | C₁₅H₁₇BrN₄O₅S |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Macitentan |
| Purity | >98% |
| Smileys | O=[S](NC1=NC=NC(OCC(O)=O)=C1C2=CC=C(Br)C=C2)(NCCC)=O |
| Canonical Smiles | CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCC(=O)O)C2=CC=C(C=C2)Br |
| InchIKey | IMSGHDWVBCDHNU-UHFFFAOYSA-N |
| Inchl | InChI=1S/C15H17BrN4O5S/c1-2-7-19-26(23,24)20-14-13(10-3-5-11(16)6-4-10)15(18-9-17-14)25-8-12(21)22/h3-6,9,19H,2,7-8H2,1H3,(H,21,22)(H,17,18,20) |
| IUPAC | 2-[5-(4-bromophenyl)-6-(propylsulfamoylamino)pyrimidin-4-yl]oxyacetic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Macitentan ACT-373898 is a medication that is prescribed to treat pulmonary arterial hypertension (PAH). This condition occurs when the blood vessels in the lungs narrow, making it difficult for blood to flow through them effectively. This can lead to shortness of breath, fatigue, and other symptoms. Macitentan works by blocking the effects of a hormone called endothelin, which causes blood vessels to constrict.
Macitentan is available in tablet form and is typically taken once a day. The dosage may vary depending on the severity of the condition and other factors such as age and weight. It is important to follow the instructions provided by your doctor and never exceed the recommended dose.
In terms of chemical information, Macitentan belongs to a class of drugs called endothelin receptor antagonists. It has a molecular weight of 588.72 g/mol and a chemical formula of C19H20Br2N6O4S. The drug is primarily metabolized in the liver and excreted through the feces.
Like any medication, Macitentan can have side effects. Common side effects include headache, nausea, and swelling in the legs and ankles. More serious side effects can include liver damage and decreased blood cell count. It is important to discuss any concerns or questions you may have with your doctor before starting this medication.
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Related Compounds
S-Despropylamino S-Methyl Macitentan | N-Despropyl-N-Ethyl Macitentan | Hydroxy N-Propyl Impurity | N-Nitroso Macitentan Dimer Impurity | N-[5-(4-Bromophenyl)-6-[2-chloroethoxy]-4-pyrimidinyl]-N'-propylsulfamide | N-Nitroso Macitentan | O-Desbromo-pyrimidinyl Macitentan | Macitentan Impurity 2 | Macitentan Impurity C | Macitentan Impurity 1 | Macitentan Pyrimidine N-Propyl | DiDesbromo Dichloro Macitentan impurity | N-Nitroso Macitentan Impurity 19 | Macitentan Impurity A | N-Despropyl-N-methyl Macitentan | N-Nitroso Macitentan Impurity 21 | Macitentan Isopropyl Impurity | Macitentan Impurity 22 | Macitentan Impurity 3 | N-Despropyl-N-ethyl Macitentan | Macitentan Impurity 5 |