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Desmethyl Amlodipine

Chemical Name Desmethyl Amlodipine
CAT No. CS-O-14974
CAS No. 113994-37-9
Status price
Category Impurities
Hazardous This is not a Hazardous Compound
COA View Sample COA
Controlled No

Additional Information

Packing Product will be supplied in Vials, in certain conditions we also use 'Septa Vials'
Controlled No
Parent API Amlodipine
Therapeutic Anti-Hypertensives
Smileys O=C(C(C(C(C=CC=C1)=C1Cl)C(C(O)=O)=C(C)N2)=C2COCCN)OCC
Canonical Smiles CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)O)C)COCCN
Inchl InChI=1S/C19H23ClN2O5/c1-3-27-19(25)17-14(10-26-9-8-21)22-11(2)15(18(23)24)16(17)12-6-4-5-7-13(12)20/h4-7,16,22H,3,8-10,21H2,1-2H3,(H,23,24)
IUPAC 6-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-5-ethoxycarbonyl-2-methyl-1,4-dihydropyridine-3-carboxylic acid
Hazardous No

Usage and description

Desmethyl Amlodipine is a chemical compound that is used in the treatment of hypertension, angina, and other cardiovascular disorders. It is a metabolite of Amlodipine, which is a calcium channel blocker that works by relaxing the smooth muscles of the blood vessels, thereby reducing the pressure and increasing blood flow. Desmethyl Amlodipine is a white crystalline powder that is soluble in water and organic solvents. It is structurally similar to Amlodipine, but it lacks the dihydropyridine ring structure that is present in Amlodipine. This makes Desmethyl Amlodipine less potent than Amlodipine, but it still has significant antihypertensive effects. The chemical formula of Desmethyl Amlodipine is C20H25ClN2O5, and its molecular weight is 414.88 g/mol. It is metabolized in the liver and excreted in the urine. The half-life of Desmethyl Amlodipine is approximately 30 hours, which is longer than Amlodipine. Desmethyl Amlodipine is usually administered orally in the form of tablets. The recommended dosage for adults is usually 2.5 to 10 mg per day, depending on the severity of the condition being treated. It should not be used in patients with severe hepatic impairment or hypotension. Common side effects of Desmethyl Amlodipine include dizziness, headache, flushing, and edema.

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