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Amiloride 15N3 Hydrochloride

Chemical Name Amiloride 15N3 Hydrochloride
CAT No. CS-O-15078
CAS Registry# 1216796-18-7
Status Prompt Dispatch
Category Stable Isotopes
Mol. Wt. 269.07 g/mol
Mol. For. C₆H₉Cl₂N₄¹⁵N₃O
Hazardous This is a Hazardous Compound
COA View Sample COA

Additional Information

Controlled No
Parent API Amiloride
Purity Not less than 95 %
Therapeutic Anti-Hypertensives
Smileys O=C(C1=NC(Cl)=C(N)N=C1N)[15NH]C([15NH2])=[15NH].Cl
Canonical Smiles C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.Cl
Inchl InChI=1S/C6H8ClN7O.ClH/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;/h(H4,8,9,13)(H4,10,11,14,15);1H/i10+1,11+1,14+1;
IUPAC 3,5-diamino-N-[bis(15N)(azanyl)methylidene]-6-chloropyrazine-2-(15N)carboxamide;hydrochloride
Hazardous Yes

Usage and description

Amiloride 15N3 Hydrochloride is an orally administered medication that is primarily used as a diuretic to treat hypertension and heart failure. It works by blocking the sodium channels in the kidneys, which reduces the amount of sodium reabsorbed into the bloodstream. This leads to increased water excretion and reduced blood volume, which helps to lower blood pressure. In addition to its diuretic properties, Amiloride 15N3 Hydrochloride has also been shown to have anti-inflammatory effects and may be helpful in treating certain types of kidney disease. It is typically prescribed in tablet form and is taken once or twice daily, depending on the patient's needs. Chemically, Amiloride 15N3 Hydrochloride is a derivative of the pyrazinecarboxamide class of compounds. It has a molecular weight of 302.81 g/mol and a chemical formula of C6H8ClN7O•HCl. The compound contains three nitrogen atoms, all of which are labeled with the stable isotope 15N. This makes it useful for research studies that require the use of isotopically labeled compounds. Amiloride 15N3 Hydrochloride is generally well-tolerated by patients, although it may cause mild side effects such as nausea, dizziness, and headache. It should not be used by individuals with severe kidney disease or hyperkalemia (high potassium levels). As with any medication, it is important to follow the dosage instructions provided by your healthcare provider and to report any adverse effects.

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