Losartan N1-Trityl Impurity
| Product Name | Losartan N1-Trityl Impurity |
|---|---|
| Alternate Names | Losartan Impurities, Impurities of Losartan |
| CAT No. | CS-O-15330 |
| CAS No. | 124751-00-4 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 665.23 g/mol |
| Mol. For. | C₄₁H₃₇ClN₆O |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Losartan |
| Therapeutic | Anti-Hypertensives |
| Smileys | CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=NN4C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)CO)Cl |
| Canonical Smiles | CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=NN4C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)CO)Cl |
| InchIKey | ZKJNVODQIYQUNQ-UHFFFAOYSA-N |
| Inchl | InChI=1S/C41H37ClN6O/c1-2-3-23-38-43-39(42)37(29-49)47(38)28-30-24-26-31(27-25-30)35-21-13-14-22-36(35)40-44-45-46-48(40)41(32-15-7-4-8-16-32,33-17-9-5-10-18-33)34-19-11-6-12-20-34/h4-22,24-27,49H,2-3,23,28-29H2,1H3 |
| IUPAC | [2-butyl-5-chloro-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Losartan N1-Trityl Impurity is a chemical compound that is used in the synthesis of Losartan, a medication that is used to treat hypertension and other cardiovascular disorders. The impurity is a byproduct of the chemical reaction that is used to produce Losartan, and it is important to monitor the levels of the impurity in the drug product to ensure its safety and efficacy.
Chemically, Losartan N1-Trityl Impurity is a trityl-protected amino acid that is formed during the synthesis of Losartan. The trityl group is a benzyl protecting group that is used to protect the amino group during the synthesis. The impurity is typically removed during the purification process, but trace amounts may remain in the final drug product.
The presence of Losartan N1-Trityl Impurity in the final drug product can potentially affect its safety and efficacy. Therefore, regulatory agencies such as the FDA have set limits on the allowable levels of the impurity in Losartan products. Manufacturers of Losartan must ensure that the levels of this impurity are within acceptable limits before the drug is released to the market.
In conclusion, Losartan N1-Trityl Impurity is an important chemical compound that is closely monitored during the production of Losartan. Its presence in the final drug product can affect its safety and efficacy, and manufacturers must ensure that its levels are within acceptable limits before releasing the drug to the market.
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Related Compounds
N-Trityl Losartan Carboxylic Acid | Losartan Potassium EP Impurity E | Losartan EP Impurity C | Losartan Amine | Losartan isocyano Impurity | Losartan Impurity 1 | Losartan Impurity 8 | N-Trityl Losartan Isomer | Losartan Potassium EP Impurity A | Losartan EP Impurity F | Losartan Hydroxy N1-Trityl Impurity | Nitroso Losartan | Losartan Related Compound D | Losartan EP Impurity B | Losartan Impurity 7 | Losartan Impurity 6 | Losartan Impurity 5 | Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde | Losartan Related Compound E | Losartan Imidazo[1,5-b]isoquinoline Impurity | N-Trityl Losartan Carboxaldehyde | Losartan Potassium EP Impurity H | Losartan Potassium EP Impurity J | Losartan a-Butyl-losartan Aldehyde Adduct | Losartan Dimer Azide | Losartan Impurity 29 | Losartan Potassium EP Impurity K | Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan | Losartan EP Impurity M | Losartan EP Impurity L | Losartan Impurity 15 | Losartan Acetyloxy N1-Trityl Impurity | Losartan Potassium EP Impurity C | Losartan Acetyloxy Impurity | Losartan Azide impurity |