Product Name |
Atovaquone Indene Isomer |
Alternate Names |
Atovaquone Impurities, Impurities of Atovaquone |
CAT No. |
CS-O-15476
|
CAS No. |
Not Available |
Category |
Impurities |
Stock |
IN-Stock
|
Mol. Wt. |
366.84 g/mol |
Mol. For. |
C₂₂H₁₉ClO₃
|
Hazardous |
This is a Hazardous Compound
|
COA |
View Sample COA
|
MSDS |
View Sample MSDS
|
Parent API |
Atovaquone |
Purity |
95% |
Smileys |
O=C(C(C1=C2C=CC=C1)=C([C@H]3CC[C@H](C4=CC=C(Cl)C=C4)CC3)C2=O)O |
Controlled |
No |
Shipping |
Free for purchase above 1000$ |
Delivery |
In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
Return |
Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
Ordering |
Place your order online or by email sales@clearsynth.com |
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Atovaquone Indene Isomer is a chemical compound that has been used for its antiprotozoal and antimalarial properties. It is an isomer of Atovaquone, which is a commonly used antimalarial drug. Atovaquone Indene Isomer is a potent inhibitor of the mitochondrial electron transport chain in Plasmodium falciparum, the causative agent of malaria. It is also active against other protozoa such as Toxoplasma gondii and Pneumocystis jirovecii.
Atovaquone Indene Isomer is usually administered in combination with other drugs, such as proguanil, to increase its efficacy and prevent the development of drug resistance. It is available in tablet form and is taken orally. The dosage and duration of treatment depend on the severity of the infection and the patient's age and weight.
The chemical formula of Atovaquone Indene Isomer is C22H19ClO3, and its molecular weight is 376.84 g/mol. It is a white to off-white crystalline powder that is sparingly soluble in water but soluble in methanol and ethanol. The compound has a melting point of 158-160°C.
Atovaquone Indene Isomer is a synthetic compound that was first synthesized in the 1990s by GlaxoSmithKline. It works by inhibiting the cytochrome bc1 complex in the mitochondrial electron transport chain, thereby disrupting the production of ATP and leading to the death of the parasite. The compound has a relatively low toxicity profile and is generally well-tolerated by patients. However, it may cause gastrointestinal side effects such as nausea, vomiting, and diarrhea.