Azathioprine-d3

Product Name Azathioprine-d3
Alternate Names Azathioprine Stable Isotopes, Stable Isotopes of Azathioprine
CAT No. CS-O-15630
CAS No. 446-86-6(Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 280.28 g/mol
Mol. For. C₉H₄D₃N₇O₂S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Azathioprine
Purity Not less than 95 %
Therapeutic Immunosuppressants
Smileys O=[N+]([O-])C(N=C1)=C(N1C([2H])([2H])[2H])SC(NC=N2)=C3C2=NC=N3
Controlled No
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Azathioprine-d3 is a deuterated form of azathioprine, an immunosuppressive drug used to treat a range of autoimmune disorders. The deuterated version of the drug is chemically identical to the regular form of azathioprine, except that three of the hydrogen atoms have been replaced with deuterium atoms. This modification does not affect the drug's therapeutic properties, but it does make it easier to track and analyze in biological systems. Azathioprine-d3 works by inhibiting the production of DNA and RNA in cells of the immune system, which reduces their ability to proliferate and attack healthy tissues. This makes it an effective treatment for conditions such as rheumatoid arthritis, lupus, and inflammatory bowel disease. It can also be used in combination with other drugs to prevent organ rejection in transplant patients. Like the regular form of azathioprine, azathioprine-d3 is metabolized in the liver and excreted in the urine. It has a half-life of approximately 3-5 hours and is typically administered orally once or twice a day. Monitoring of blood cell counts and liver function is necessary during treatment with this drug. Overall, azathioprine-d3 is a valuable tool for researchers studying the pharmacokinetics and pharmacodynamics of azathioprine, as well as for clinicians treating patients with autoimmune disorders and transplant recipients.

Related Compounds

Azathioprine 13C4 | Azathioprine-13C2-15N |

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