Panobinostat D4
| Product Name | Panobinostat D4 |
|---|---|
| CAT No. | CS-O-15678 |
| CAS No. | 404950-80-7 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 353.45 g/mol |
| Mol. For. | C₂₁H₁₉D₄N₃O₂ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CC1=C(C2=C([2H])C([2H])=C([2H])C([2H])=C2N1)CCNCC3=CC=C(/C=C/C(NO)=O)C=C3 |
| Canonical Smiles | CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO |
| InchIKey | FPOHNWQLNRZRFC-ZHACJKMWSA-N |
| Inchl | InChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+ |
| IUPAC | (E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Panobinostat D4 is a deuterated analog of the histone deacetylase inhibitor Panobinostat. It is a potent oral anticancer drug that is used for the treatment of multiple myeloma. Panobinostat D4 works by inhibiting the activity of histone deacetylases, which in turn leads to the accumulation of acetylated histones. This accumulation modulates the expression of genes that are involved in cellular growth, differentiation, and apoptosis.
Panobinostat D4 is administered orally and is rapidly absorbed, with peak plasma concentrations occurring within 2-4 hours of dosing. It has a half-life of approximately 37 hours. The drug is extensively metabolized in the liver by CYP3A4 and is excreted in the feces and urine.
Panobinostat D4 is a small molecule that belongs to the hydroxamic acid class of compounds. Its chemical formula is C21H23D4N2O3 and its molecular weight is 391.5 g/mol. The drug is a white to off-white powder that is practically insoluble in water and slightly soluble in ethanol and methanol.
In conclusion, Panobinostat D4 is a powerful anticancer drug that is used for the treatment of multiple myeloma. It works by inhibiting histone deacetylases and modulating the expression of genes that are involved in cellular growth, differentiation, and apoptosis. Its chemical properties make it a unique and promising compound for cancer treatment.
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