Tenofovir Alafenamide-d5
| Product Name | Tenofovir Alafenamide-d5 |
|---|---|
| Alternate Names | Tenofovir Stable Isotopes, Stable Isotopes of Tenofovir |
| CAT No. | CS-O-15682 |
| CAS No. | 379270-36-7 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 481.50 g/mol |
| Mol. For. | C₂₁H₂₄D₅N₆O₅P |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Tenofovir |
| Purity | Not less than 90 % |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | C[C@@H](OC[P](OC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])(N[C@@H](C)C(OC(C)C)=O)=O)CN2C3=NC=NC(N)=C3N=C2 |
| Canonical Smiles | CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3 |
| InchIKey | LDEKQSIMHVQZJK-DCEZVVCRSA-N |
| Inchl | InChI=1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)/t15-,16?,33?/m1/s1 |
| IUPAC | propan-2-yl 2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Tenofovir Alafenamide-d5 is a deuterated form of Tenofovir Alafenamide (TAF), which is an antiviral medication used to treat human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections. TAF is a prodrug of tenofovir, which means that it is converted to tenofovir in the body to exert its antiviral effect. Tenofovir is a nucleotide analogue that inhibits the reverse transcriptase enzyme, thereby blocking viral replication.
Tenofovir Alafenamide-d5 is used in clinical research to investigate the pharmacokinetics and pharmacodynamics of TAF in the body. It is a stable isotope-labelled compound that allows researchers to track the metabolic fate of TAF in vivo, as well as to quantitate TAF levels in biological samples using mass spectrometry.
The chemical formula of Tenofovir Alafenamide-d5 is C21H18D5N6O5P, and its molecular weight is 480.49 g/mol. It has the same mechanism of action and pharmacological properties as TAF, but its deuterated structure provides a unique tool for drug development and research.
In summary, Tenofovir Alafenamide-d5 is a valuable research tool for investigating the pharmacokinetics and pharmacodynamics of TAF, a potent antiviral medication used to treat HIV and HBV infections. Its stable isotope-labelled structure allows for sensitive and quantitative analysis of TAF levels in biological samples, which can aid in the development of new antiviral therapies.
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Related Compounds
Tenofovir Alafenamide-d5 Fumarate (diastereomers) | Tenofovir Alafenamide D6 | Tenofovir disoproxil D12 fumarate | rac Tenofovir-d6 Diphosphate Triethylamine Salt (mixture of diastereomers) | Tenofovir Disoproxil-d6 Fumarate | Tenofovir-d5 | Desphenyl Tenofovir Alafenamide-d7 Ammonium Salt | rac Tenofovir-d6 | Tenofovir D6 | rac-Tenofovir D7 |