Apremilast impurity D
| Product Name | Apremilast impurity D |
|---|---|
| Alternate Names | Apremilast Impurities, Impurities of Apremilast |
| CAT No. | CS-O-15764 |
| CAS No. | 253168-87-5 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 474.53 g/mol |
| Mol. For. | C₂₃H₂₆N₂O₇S |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Apremilast |
| Smileys | CC(NC1=CC=CC(C(N2C(C3=CC=C(OCC)C(OCC)=C3)CS(=O)(C)=O)=O)=C1C2=O)=O |
| Canonical Smiles | CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C=C(C=C3)NC(=O)C)OC |
| InchIKey | MBKPNNHJNFQTAP-UHFFFAOYSA-N |
| Inchl | InChI=1S/C22H24N2O7S/c1-5-31-20-10-14(6-9-19(20)30-3)18(12-32(4,28)29)24-21(26)16-8-7-15(23-13(2)25)11-17(16)22(24)27/h6-11,18H,5,12H2,1-4H3,(H,23,25) |
| IUPAC | N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-5-yl]acetamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Apremilast impurity D, also known as N-(2,6-difluorophenyl)-2-[(1-methyl-1H-pyrazol-5-yl)amino]acetamide, is a chemical compound that is used in the pharmaceutical industry as an impurity in the production of Apremilast, which is a drug used to treat psoriasis and psoriatic arthritis.
The usage of Apremilast impurity D is primarily as a reference standard to ensure the purity of the final product, Apremilast. It is important to ensure the purity of the final product as impurities can affect the efficacy and safety of the drug.
In terms of chemical information, Apremilast impurity D has the molecular formula C15H13F2N4O and a molecular weight of 314.29 g/mol. It is a white to off-white crystalline powder that is soluble in organic solvents such as methanol, ethanol and DMSO.
The synthesis of Apremilast impurity D involves the reaction between 2-amino-5-methyl-1H-pyrazole and 2,6-difluoroaniline in the presence of a coupling agent such as N,N'-diisopropylcarbodiimide (DIC) and catalytic amount of 4-dimethylaminopyridine (DMAP). The resulting product is then purified by recrystallization or chromatography.
Overall, Apremilast impurity D plays a crucial role in ensuring the quality and purity of Apremilast, which is an important drug in the treatment of psoriasis and psoriatic arthritis.
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Related Compounds
Apremilast Impurity 77 | Apremilast Enantiomer | Desacetyl Apremilast benzoic acid Impurity | Methyl Hydroxy Apremilast | Apremilast Impurity 17 | Apremilast Acetamido Sulfone Impurity | Apremilast Degradation Impurity -2 | Apremilast Impurity C | Apremilast Impurity 15 | Apremilast Impurity 8 | Apremilast Impurity H | Apremilast Impurity F | Apremilast Impurity 10 | Apremilast Impurity B | Apremilast Impurity 2 | Apremilast Impurity 18 | Apremilast pseudo dimer impurity | Desacetyl Apremilast | O4-Desmethyl O3-Desethyl Apremilast | N-Desacetyl O4-Desmethyl Apremilast | Apremilast Isopropyl alcohol Impurity | Apremilast 2-hydroxyethyl-sulfonyl impurity | Desoxo Apremilast | Apremilast Desoxo impurity | N-Desacetyl O4-Desmethyl O3-Desethyl Apremilast | Apremilast Dimer | Diethoxy Rac-Apremilast Impurity | Apremilast Dimer |