(4S)-3-[(4E)-5-(4-fluorophenyl)pent-4-enoyl]-4-phenyl-1,3-oxazolidin-2-one

(4S)-3-[(4E)-5-(4-fluorophenyl)pent-4-enoyl]-4-phenyl-1,3-oxazolidin-2-one, also known as F-Phe-Oxa-4, is a synthetic compound used in medicinal chemistry research. It is a member of the oxazolidinone family of antibiotics, which are used to treat bacterial infections. The chemical structure of F-Phe-Oxa-4 contains an oxazolidinone ring, which is a five-membered heterocyclic ring composed of oxygen, nitrogen, and carbon atoms. This ring is known for its ability to inhibit bacterial protein synthesis by binding to the ribosome. The addition of the fluorophenyl and pent-4-enoyl groups to the oxazolidinone ring enhances the compound's antibacterial activity. F-Phe-Oxa-4 has been shown to be effective against a wide range of bacterial species, including those that are resistant to other antibiotics. It has been studied for its potential use in treating infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). The compound has also been investigated for its ability to penetrate the blood-brain barrier, making it a potential candidate for treating central nervous system infections. In summary, F-Phe-Oxa-4 is a synthetic compound with potent antibacterial activity, making it a valuable tool for researchers studying bacterial infections and potential treatments.