Abiraterone Ethyl Ether D5

Abiraterone Ethyl Ether D5 is a deuterated analog of abiraterone acetate, which is a potent and selective inhibitor of CYP17A1, a key enzyme involved in androgen biosynthesis. Abiraterone Ethyl Ether D5 is used in research studies to investigate the metabolic fate and pharmacokinetics of abiraterone acetate in vivo. Abiraterone acetate is used clinically in the treatment of metastatic castration-resistant prostate cancer, as it inhibits androgen production both in the testes and in the tumor microenvironment. The addition of deuterium atoms to Abiraterone Ethyl Ether D5 provides a useful tool for studying the metabolism and pharmacokinetics of abiraterone acetate in vivo, as it allows for the discrimination of different metabolites and the quantification of their concentrations. Chemically, Abiraterone Ethyl Ether D5 is a deuterated derivative of abiraterone acetate, with the same basic molecular structure but with the addition of five deuterium atoms. It has a molecular formula of C26H38D5NO2 and a molecular weight of 424.68 g/mol. Abiraterone Ethyl Ether D5 is a white to off-white powder that is soluble in organic solvents such as ethanol, methanol, and DMSO. In conclusion, Abiraterone Ethyl Ether D5 is a useful tool for studying the pharmacokinetics and metabolism of abiraterone acetate in vivo. Its deuterium-labeled structure allows for the identification and quantification of different metabolites, which can help to improve our understanding of how abiraterone acetate works in the body and how it can be used more effectively in the treatment of prostate cancer.