Ezetimibe D4
| Product Name | Ezetimibe D4 |
|---|---|
| Alternate Names | Ezetimibe Stable Isotopes, Stable Isotopes of Ezetimibe |
| CAT No. | CS-O-16105 |
| CAS No. | 1093659-90-5 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 413.45 g/mol |
| Mol. For. | C₂₄H₁₇D₄F₂NO₃ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Ezetimibe |
| Purity | 95% |
| Therapeutic | Anti-Hyperlipidemics |
| Smileys | C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O |
| Canonical Smiles | C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O |
| InchIKey | OLNTVTPDXPETLC-ARVCERDTSA-N |
| Inchl | InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1/i7D,8D,9D,10D |
| IUPAC | (3R,4S)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-(2,3,5,6-tetradeuterio-4-fluorophenyl)azetidin-2-one |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Ezetimibe D4, also known as Fluoroaniline - d4, is a deuterated analog of Ezetimibe, which is a drug used to lower cholesterol levels in the blood. This compound is a selective inhibitor of intestinal cholesterol absorption and is used in combination with diet and exercise to treat hypercholesterolemia. The deuterated form of Ezetimibe allows for more accurate analysis in research and clinical studies.
Ezetimibe D4 is a white crystalline powder that is soluble in organic solvents such as methanol and ethanol. It has a molecular weight of 420.6 g/mol and a chemical formula of C24H21D4F2NO3. The deuterated form of Ezetimibe has the same chemical structure as the non-deuterated form, but with four of the hydrogen atoms replaced with deuterium.
The mechanism of action of Ezetimibe D4 involves inhibition of the Niemann-Pick C1-like 1 (NPC1L1) protein in the small intestine. This protein is responsible for the uptake of dietary cholesterol and other sterols from the intestinal lumen into enterocytes. By inhibiting this protein, Ezetimibe D4 reduces the absorption of cholesterol and other sterols from the diet, leading to a decrease in total cholesterol levels in the blood.
In conclusion, Ezetimibe D4 is a deuterated analog of Ezetimibe that is used in research and clinical studies. It is a selective inhibitor of intestinal cholesterol absorption and helps to lower cholesterol levels in the blood. Its chemical structure, mechanism of action, and solubility in organic solvents make it a valuable tool in cholesterol-lowering research.
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Related Compounds
Ezetimibe D4 (4-Fluorophenyl-2,3,5,6-d4) | Ezetimibe Hydroxy-d4 β-D-Glucuronide | Rac Ezetimibe D4 | Ezetimibe N-Phenyl-D4 Phenoxy Glucuronide | Ezetimibe-D4 Phenoxy Glucuronide | Ezetimibe-d4 Diacetate | Ezetimibe 13C6 |