Sacubitrilat D4
| Product Name | Sacubitrilat D4 |
|---|---|
| Alternate Names | Sacubitril Stable Isotopes, Stable Isotopes of Sacubitril |
| CAT No. | CS-O-16369 |
| CAS No. | 149709-44-4(Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 387.46 g/mol |
| Mol. For. | C₂₂H₂₁D₄NO₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Sacubitril |
| Purity | 95% |
| Smileys | O=C(C([2H])([2H])C([2H])([2H])C(O)=O)N[C@@H](C[C@@H](C)C(O)=O)CC1=CC=C(C2=CC=CC=C2)C=C1 |
| Canonical Smiles | CC(CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O)C(=O)O |
| InchIKey | DOBNVUFHFMVMDB-BEFAXECRSA-N |
| Inchl | InChI=1S/C22H25NO5/c1-15(22(27)28)13-19(23-20(24)11-12-21(25)26)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-10,15,19H,11-14H2,1H3,(H,23,24)(H,25,26)(H,27,28)/t15-,19+/m1/s1 |
| IUPAC | (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Sacubitrilat D4 is a deuterated analog of Sacubitrilat, which is a prodrug metabolite of Sacubitril, an angiotensin receptor neprilysin inhibitor (ARNI) used for the treatment of heart failure. Sacubitrilat D4 is a stable isotopic labelled compound used in clinical research and development to study the pharmacokinetics, metabolism, and drug interactions of Sacubitrilat.
Sacubitrilat D4 is an organic compound with a molecular formula C24H26D4N2O5 and a molecular weight of 443.55 g/mol. It is a white to off-white crystalline powder that is soluble in dimethyl sulfoxide, methanol, and water.
As an ARNI, Sacubitrilat D4 works by inhibiting the angiotensin receptor and neprilysin, which are two enzymes that play a role in regulating blood pressure and fluid balance in the body. By inhibiting these enzymes, Sacubitrilat D4 helps to reduce the workload on the heart and improve heart function in patients with heart failure.
The usage of Sacubitrilat D4 is primarily in clinical research and development. It is used as a stable isotopic labelled compound to study the pharmacokinetics, metabolism, and drug interactions of Sacubitrilat. The information gathered from these studies helps to improve the safety and efficacy of Sacubitrilat and guide its clinical use.
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Related Compounds
Sacubitrilat-13C4 | Sacubitril D4 Calcium Salt | Sacubitril 13C4 Calcium | Sacubitril metabolite LBQ657 13C4 | Sacubitril 13C4 | Sacubitril D4 |