Desmethylleucyl Vancomycin
| Product Name | Desmethylleucyl Vancomycin |
|---|---|
| Alternate Names | Vancomycin Impurities, Impurities of Vancomycin |
| CAT No. | CS-O-16450 |
| CAS No. | 115236-65-2 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 1322.07 g/mol |
| Mol. For. | C₅₉H₆₂Cl₂N₈O₂₃ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Vancomycin |
| Therapeutic | Antibiotics |
| Smileys | CC1C(C(CC(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C7C(=O)NC(C8=C(C(=CC(=C8)O)O)C9=C(C=CC(=C9)C(C(=O)N7)NC(=O)C5NC(=O)C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)N)CC(=O)N)O)C(=O)O)O)Cl)CO)O)O)(C)N)O |
| Canonical Smiles | CC1C(C(CC(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C7C(=O)NC(C8=C(C(=CC(=C8)O)O)C9=C(C=CC(=C9)C(C(=O)N7)NC(=O)C5NC(=O)C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)N)CC(=O)N)O)C(=O)O)O)Cl)CO)O)O)(C)N)O |
| InchIKey | SSCUQZZTTLVMFJ-LCEIAXBHSA-N |
| Inchl | InChI=1S/C59H62Cl2N8O23/c1-19-51(79)59(2,64)17-38(87-19)91-50-48(78)47(77)36(18-70)90-58(50)92-49-34-12-23-13-35(49)89-33-8-5-22(11-28(33)61)46(76)44-56(84)68-43(57(85)86)26-14-24(71)15-31(73)39(26)25-9-20(3-6-30(25)72)41(54(82)69-44)67-55(83)42(23)66-52(80)29(16-37(62)74)65-53(81)40(63)45(75)21-4-7-32(88-34)27(60)10-21/h3-15,19,29,36,38,40-48,50-51,58,70-73,75-79H,16-18,63-64H2,1-2H3,(H2,62,74)(H,65,81)(H,66,80)(H,67,83)(H,68,84)(H,69,82)(H,85,86)/t19-,29-,36+,38-,40+,41+,42+,43-,44-,45+,46+,47+,48-,50+,51+,58-,59-/m0/s1 |
| IUPAC | (1S,2R,18R,19R,22S,25R,28R,40S)-19-amino-48-[(2S,3R,4S,5S,6R)-3-[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Desmethylleucyl Vancomycin (DMV) is a modified version of the antibiotic Vancomycin, which is commonly used to treat serious bacterial infections. DMV has been developed to address the growing concern of antibiotic resistance, as it has been shown to be effective against bacteria that are resistant to traditional Vancomycin.
DMV works by binding to the bacterial cell wall and inhibiting the growth and replication of bacteria. This is achieved through the modification of the Vancomycin molecule, which allows it to penetrate the cell wall more effectively and bind to a wider range of bacterial targets.
In terms of chemical information, DMV has a molecular weight of 1,449.68 g/mol and a chemical formula of C66H96Cl2N12O26. It is a glycopeptide antibiotic, which means it is composed of a peptide chain attached to a sugar molecule.
DMV is typically administered intravenously in hospital settings and is used to treat infections caused by multi-drug resistant bacteria, such as MRSA (methicillin-resistant Staphylococcus aureus) and VRE (vancomycin-resistant Enterococcus). Clinical studies have shown that DMV is well-tolerated and effective in treating these infections.
Overall, DMV represents an important development in the fight against antibiotic resistance and offers a promising new treatment option for serious bacterial infections.
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Related Compounds
Vancomycin EP Impurity D | Vancomycin CDP-1 | Vancomycin EP Impurity I | Vancomycin RS-2- Impurity | N-Methylleucyl Vancomycin | alfa-Avoparcin | Vancomycin EP Impurity A | beta-Avoparcin | Vancomycin B | N,N-Dimethyl-N-(3-(octylamino)propyl)-vancomycin Carboxamide hydrochloride salt | Vancomycin EP Impurity B | Vancomycin EP Impurity K | Vancomycin Impurity B2 | N-desmethyl Vancomycin | N,N-Dimethyl-N-(3-(tetradecylamino)propyl)-vancomycin Carboxamide hydrochloride salt | Vancomycin RS-1- Impurity | Vancomycin EP Impurity E | Vancomycin Hexapeptide | Vancomycin EP Impurity G HCl | Vancomycin Impurity-G | Vancomycin EP Impurity H | Vancomycin EP Impurity J | Vancomycin Didechloro Impurity | Vancomycin Impurity-F | epi-26-Vancomycin B | Vancomycin RS-3- Impurity | Vancomycin Impurity-L | Vancomycin EP Impurity C |