Sacubitril D4 Calcium Salt
| Product Name | Sacubitril D4 Calcium Salt |
|---|---|
| Alternate Names | Sacubitril Stable Isotopes, Stable Isotopes of Sacubitril |
| CAT No. | CS-O-16522 |
| CAS No. | 1369773-39-6 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 434.55 g/mol |
| Mol. For. | C₂₄H₂₄D₄Ca₀.₅NO₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Sacubitril |
| Purity | Not less than 98% |
| Smileys | O=C(OCC)[C@H](C)CC(NC(C([2H])([2H])C([2H])([2H])C([O-])=O)=O)CC1=CC=C(C2=CC=CC=C2)C=C1 |
| Canonical Smiles | CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)[O-].[Ca+2] |
| InchIKey | DDLCKLBRBPYKQS-OXXXZDCLSA-L |
| Inchl | InChI=1S/2C24H29NO5.Ca/c2*1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19;/h2*4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28);/q;;+2/p-2/t2*17-,21+;/m11./s1 |
| IUPAC | calcium;4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Sacubitril D4 Calcium Salt is a deuterated form of sacubitril calcium, which is a medication used for the treatment of heart failure. Sacubitril D4 Calcium Salt is an angiotensin receptor neprilysin inhibitor (ARNI), which means it works by blocking the angiotensin II receptor and inhibiting the enzyme neprilysin. By doing so, it reduces the amount of vasoconstrictive hormones and increases the levels of vasodilatory hormones, leading to an increase in the blood flow to the heart and a decrease in cardiac workload.
The usage of Sacubitril D4 Calcium Salt is primarily for the treatment of chronic heart failure with reduced ejection fraction. It is usually taken orally, and the dosage is determined by the healthcare provider based on the patient's age, medical history, and other medications being taken. The medication is generally well-tolerated, but some side effects may occur, such as low blood pressure, kidney problems, and high potassium levels.
Chemically, Sacubitril D4 Calcium Salt is a deuterated form of sacubitril calcium, which means that it contains four deuterium atoms instead of hydrogen atoms. This modification improves the bioavailability and stability of the medication. The calcium salt form of sacubitril is used to improve the solubility and absorption of the medication in the body. Overall, Sacubitril D4 Calcium Salt is a vital medication for the treatment of heart failure, and its chemical modification enhances its therapeutic efficacy.
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Related Compounds
Sacubitril 13C4 | Sacubitrilat-13C4 | Sacubitril D4 | Sacubitril metabolite LBQ657 13C4 | Sacubitril 13C4 Calcium | Sacubitrilat D4 |